Evidence map›Paper›PMID 25360077›Full record

ArticleImmune network2014

Effects of Endurance Training on the Serum Levels of Tumour Necrosis Factor-α and Interferon-γ in Sedentary Men.

Abdolreza Sotoodeh Jahromi, Abdossaleh Zar, Fatemeh Ahmadi, Peter Krustrup, Khosrow Ebrahim, Friborz Hovanloo, Davar Amani

Open access · hybridAbstract read
In one paragraph

Article in Immune network, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Abdolreza Sotoodeh JahromiResearch Center for Non.communicable Diseases, Immunology Department, Jahrom University of Medical Sciences, Jahrom, Iran.
Abdossaleh ZarDepartment of Physical Education & Sport Science,University of Jahrom, Jahrom, Iran.
Fatemeh AhmadiDepartment of Physical Education & Sport Sciences, Shiraz University, Shiraz, Iran.
Peter KrustrupSport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
Khosrow EbrahimDepartment of Exercise Physiology, G.C. Shahid Beheshti University, Tehran, Iran.
Friborz HovanlooDepartment of Exercise Physiology, G.C. Shahid Beheshti University, Tehran, Iran.
Davar AmaniDepartment of Immunology, Medical School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University · IRJahrom University · IRJahrom University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IRShiraz University · IRUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity could be considered one of the factors that affect the immune system status and function. To find the relation between exercise and cytokines, we examined the possible effects of an 8-week endurance training program on the serum levels of cytokines, including tumour necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) in sedentary men. A total of 30 healthy young male volunteers were randomly divided into an endurance training group and a control group. The training group followed a specific exercise protocol (running on a treadmill for 15~30 min at 50~70% maximal heart rate) for 8 weeks and the control group did not participate in any exercise program. Venous blood samples were collected from both the groups 24 h before and 24 h and 48 h after the exercise. Repeated ANOVA was used for statistical purposes. The serum levels of TNF-α and IFN-γ were determined by ELISA. Significant (p<0.05) and non-significant (p>0.05) decreases were observed in the serum levels of IFN-γ and TNF-α, respectively, after the 8-week endurance training program. Our findings indicated that an 8-week endurance exercise may affect the serum levels of some inflammatory cytokines, suggesting the beneficial role of this training protocol in elderly population and people with certain conditions (inflammation of the vertebrae or other inflammatory diseases).

Indexed as

CytokineEndurance exerciseIFN-γTNF-α

Identifiers

PMID25360077
PMCPMC4212087
OpenAlexW2026128597

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.