Evidence map›Paper›PMID 25360022›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2014

Prevalence of bacterial vaginosis and Candida among postmenopausal women in the United States.

Joscelyn N Hoffmann, Hannah M You, E C Hedberg, Jeanne A Jordan, Martha K McClintock

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Bacterial Vaginosis Decreases the Risk of Cervical Cytological Abnormalities.Cancer prevention research (Philadelphia, Pa.) · 2023
    Article
  7. Astodrimer sodium and bacterial vaginosis: a mini review.Archives of gynecology and obstetrics · 2022
    Review
  8. Article
  9. Virulence Factors ofInternational journal of molecular sciences · 2022
    Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. World journal of gastroenterology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joscelyn N HoffmannInstitute for Mind and Biology, University of Chicago, Illinois. jnhoffma@uchicago.edu.
Hannah M YouInstitute for Mind and Biology, University of Chicago, Illinois.
E C HedbergAcademic Research Centers and Education and Child Development Studies, NORC at the University of Chicago, Illinois. Sanford School of Social and Family Dynamics, Arizona State University, Tempe.
Jeanne A JordanDepartment of Epidemiology and Biostatistics, George Washington University, Washington, DC.
Martha K McClintockInstitute for Mind and Biology, University of Chicago, Illinois. Departments of Psychology and Comparative Human Development, University of Chicago, Illinois.

Funding

Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
National Social Life, Health, and Aging Project: Anaylsis of Wave 1 and Wave 2R37AG030481 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2008 to 2017
$15.4M
National Social Life, Health and Aging Project (RMI)R01AG021487 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2003 to 2007
$12.2M
NSHAP Wave II Partner Data CollectionR01AG033903 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2009 to 2013
$5.8M
NCATS NIH HHS UL1 TR000430NIA NIH HHS R01 AG021487NIA NIH HHS R01AG021487NIA NIH HHS R01 AG033903NIA NIH HHS R01AG033903NIA NIH HHS R37 AG030481NIA NIH HHS R37AG030481
6 · The paper itself

Abstract

objectivesTo describe the prevalence of bacterial vaginosis (BV) and Candida among community-dwelling postmenopausal women in the United States and determine their change with age, using estimates based on Waves 1 and 2 of the National Social Life, Health and Aging Project (NSHAP).

methodSelf-administered vaginal swabs were collected in-home from women aged 57-85 (n = 1,016) in Wave 1 and again 5 years later in Wave 2 (n = 883). Gram-stained specimens were evaluated for BV using the Nugent score as well as presence of Candida.

resultsBV was prevalent in 23% and 38% of postmenopausal women in Waves 1 and 2 and increased with age. Women initially categorized with BV in Wave 1 were more than 10 times as likely to be categorized with BV in Wave 2, relative risk ratio (RRR) = 10.5; 95% confidence interval (CI) (4.45-24.7); p < .001, whereas women initially categorized as intermediate in Wave 1 were five times more likely to have a BV categorization, RRR = 5.0; 95% CI (2.56-9.75); p < .001. Although the presence of Candida was similar in both waves (6% and 5%), its relationship with age only became evident in Wave 2, with odds of detecting Candida decreasing by 7% with each year of age, OR = 0.93, 95% CI (0.88, 0.98); p = .010. DISCUSSION: In Wave 2, the prevalence of BV was higher and increased with age while the prevalence of Candida was low and declined with age. A 5-year age increase contributed to the prevalence change across waves. Methods refinements in Wave 2 improved the detection of BV and Candida and clarified their relationship with age.

Indexed as

AgedAged, 80 and overAge FactorsCandidiasis, VulvovaginalFemaleHumansLongitudinal StudiesMenopauseMiddle AgedPrevalenceRiskUnited StatesVaginosis, BacterialBacterial vaginosisCandidaPopulationPostmenopauseSelf-collectionVaginal swab.

Identifiers

PMID25360022
PMCPMC4303100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.