ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2014
Olfactory function in Wave 2 of the National Social Life, Health, and Aging Project.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 72 citations in OpenAlex.
- The Unmet Need of Olfactory Testing in Inflammatory Disorders of the Upper Airways-An EAACI Position Paper.Allergy · 2026Review
- Therapeutic effect of intranasal nicotinamide adenine dinucleotide in the restoration of olfactory dysfunction.Experimental & molecular medicine · 2026Article
- Visual search performance depends on the congruency of olfactory sensations.Scientific reports · 2025Article
- Odor of Fatty Acids: Differences in Threshold and Perception Intensity Between Sexes.Foods (Basel, Switzerland) · 2025Article
- Age-related decrease of odorant sensitivity for a selection of nine diverse molecules.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Nomogram for predicting early olfactory dysfunction in obstructive sleep apnea-hypopnea syndrome: a multicenter-based study.Frontiers in neurology · 2025Article
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- Olfactory decline develops in parallel with frailty in older US adults with obstructive lung diseases.International forum of allergy & rhinology · 2024Article
- Aging and Olfactory Training: A Scoping Review.Innovation in aging · 2024Article
- Association ofNeurology · 2023Article
- Comparable responses to a wide range of olfactory stimulation in women and men.Scientific reports · 2023Article
- Association among Olfactory Function, Lifestyle and BMI in Female and Male Elderly Subjects: A Cross-Sectional Study.Nutrients · 2023Article
- Olfactory Function and Olfactory Disorders.Laryngo- rhino- otologie · 2023Article
- Can Digital Communication Protect Against Depression for Older Adults With Hearing and Vision Impairment During COVID-19?The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Olfaction and Anxiety Are Differently Associated in Men and Women in Cognitive Physiological and Pathological Aging.Journal of clinical medicine · 2023Article
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- Normative data for the Vietnamese smell identification test.Clinical parkinsonism & related disorders · 2023Article
- Androstadienone sensitivity is associated with attention to emotions, social interactions, and sexual behavior in older U.S. adults.PloS one · 2023Article
- Olfactory Sensitivity Is Associated with Body Mass Index and Polymorphism in the Voltage-Gated Potassium ChannelsNutrients · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo investigate the sense of smell, including sensitivity and odor identification, and characterize the U.S. national prevalence of olfactory dysfunction in older adults, thereby facilitating further investigation of the substantial risks for older adults associated with this basic sensory ability.
methodThe sense of smell was evaluated using the Olfactory Function Field Exam (OFFE), a measure designed specifically for field research, which assesses 3 components of olfaction: sensitivity to n-butanol (a standard testing odorant) and androstadienone (AND, a key social odor produced by humans), as well as the ability to identify odors. Respondents were randomly selected from the National Social Life, Health, and Aging Project Wave 2 sample to receive the OFFE (n = 2,304), and 2,212 consented to participate.
resultsIn the U.S. population aged 62-90, n-butanol detection ability was significantly worse at older ages (ordinal logistic regression, p < .001); however, there was no difference in detection ability between genders (p = .60). AND detection ability was also significantly worse at older ages (p = .003), but in contrast to n-butanol, women outperformed men (p = .001). As expected, odor identification ability was worse in older people than in younger (p < .001), and women were more accurate than men (p = .001). DISCUSSION: We report for the first time 3 facets of olfactory function and its association with age and gender in a representative sample of U.S. older adults. Future analyses of these data are needed to elucidate the sense of smell's role in physical, social, and mental health with aging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.