Evidence map›Paper›PMID 25359642›Full record

ArticleJournal of the American Dental Association (1939)2014

Twenty-month follow-up of occlusal caries lesions deemed questionable at baseline: findings from the National Dental Practice-Based Research Network.

Sonia K Makhija, Gregg H Gilbert, Ellen Funkhouser, James D Bader, Valeria V Gordan, D Brad Rindal, Vibeke Qvist, Pia Nørrisgaard, National Dental PBRN Collaborative Group

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Dental Association (1939), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Efficacy of PScientific reports · 2020
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  3. Review
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  5. A dual handheld SWIR transillumination/reflectance probe for imaging lesions on tooth occlusal and proximal surfaces.Proceedings of SPIE--the International Society for Optical Engineering · 2020
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  6. Article
  7. Article
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  10. A system for simultaneous near-infrared reflectance and transillumination imaging of occlusal carious lesions.Proceedings of SPIE--the International Society for Optical Engineering · 2016
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sonia K MakhijaDr. Makhija is an associate professor, Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham, Diagnostic Sciences, 1919 7th Ave. South, SDB 115, Birmingham, Ala. 35294-0007, e-mail smakhija@uab.edu. Address correspondence to Dr. Makhija.
Gregg H GilbertDr. Gilbert is a professor and the chair, Department of Clinical and Community Sciences, School of Dentistry, University of Alabama at Birmingham.
Ellen FunkhouserDr. Funkhouser is an associate professor, Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham.
James D BaderDr. Bader is a research professor, Department of Operative Dentistry, University of North Carolina at Chapel Hill.
Valeria V GordanDr. Gordan is a professor, Department of Restorative Dental Sciences, Division of Operative Dentistry, College of Dentistry, University of Florida Health Science Center, Gainesville.
D Brad RindalDr. Rindal is a practitioner in the HealthPartners Dental Group, Minneapolis, and an investigator at the HealthPartners Institute for Education and Research, Minneapolis.
Vibeke QvistDr. Qvist is an associate professor, Department of Cariology and Endodontics, School of Dentistry, University of Copenhagen, Denmark.
Pia NørrisgaardMs. Nørrisgaard is a research assistant, Department of Cariology and Endodontics, School of Dentistry, University of Copenhagen, Denmark.
National Dental PBRN Collaborative Group

Funding

The National Dental PBRNU19DE022516 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2012 to 2018
$66.4M
Dental PBRN Network ChairU01DE016747 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GILBERT, GREGG H · 2005 to 2011
$17.3M
Dental Practice-Based Research Network Coordinating CtrU01DE016746 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FUNKHOUSER, ELLEN M · 2005 to 2011
$7.0M
NIDCR NIH HHS U01 DE016746NIDCR NIH HHS U01 DE016747NIDCR NIH HHS U01-DE-16746NIDCR NIH HHS U01-DE-16747NIDCR NIH HHS U19 DE022516NIDCR NIH HHS U19-DE-22516
6 · The paper itself

Abstract

backgroundA questionable occlusal caries (QOC) lesion can be defined as an occlusal surface with no radiographic evidence of caries, but caries is suspected because of clinical appearance. In this study, the authors report the results of a 20-month follow-up of these lesions.

methodsFifty-three clinicians from The National Dental Practice-Based Research Network participated in this study, recording lesion characteristics at baseline and lesion status at 20 months.

resultsAt baseline, 1,341 QOC lesions were examined; the treatment that was planned for 1,033 of those at baseline was monitoring (oral hygiene instruction, applying or prescribing fluoride or varnish, or both), and the remaining 308 received a sealant (n = 192) or invasive therapy (n = 116). At the 20-month visit, clinicians continued to monitor 927 (90 percent) of the 1,033 monitored lesions. Clinicians decided to seal 61 (6 percent) of the 1,033 lesions (mean follow-up, 19 months) and invasively treat 45 (4 percent) of them (mean follow-up, 15 months). Young patient age (< 18 years) (odds ratio = 3.4; 95 percent confidence interval, 1.7-6.8) and the lesion's being on a molar (odds ratio = 1.8; 95 percent confidence interval, 1.3-2.6) were associated with the clinician's deciding at some point after follow-up to seal the lesion or treat it invasively.

conclusionsAlmost all (90 percent) QOC lesions for which the treatment planned at baseline was monitoring still were planned to undergo monitoring after 20 months. This finding suggests that noninvasive management is appropriate for these lesions. PRACTICAL IMPLICATIONS: Previous study results from baseline indicated a high prevalence of QOC lesions (34 percent). Clinicians should consider long-term monitoring when making treatment decisions about these lesions.

Indexed as

Community-Based Participatory ResearchAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDenmarkDental CariesEvidence-Based DentistryFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleMiddle Agedcariesclinical researchdental cariesEvidence-based dentistrylongitudinal studymulticenter studiespractice-based researchprivate practicequestionable lesions

Identifiers

PMID25359642
PMCPMC4220241

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.