ReviewAdvances in experimental medicine and biology2014
Searching for the holy grail: temporally informative firing patterns in the rat.
Review in Advances in experimental medicine and biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- A behavioral integration mechanism underlies action timing.Science advances · 2026Article
- Temporal scaling and computing time in neural circuits: Should we stop watching the clock and look for its gears?Frontiers in behavioral neuroscience · 2022Article
- Time Distortion in Parkinsonism.Frontiers in neuroscience · 2021Article
- Interval timing, temporal averaging, and cue integration.Current opinion in behavioral sciences · 2016Article
- In Search of Oscillatory Traces of the Internal Clock.Frontiers in psychology · 2016Article
- Hippocampus, time, and memory--a retrospective analysis.Behavioral neuroscience · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
This chapter reviews our work from the past decade investigating cortical and striatal firing patterns in rats while they time intervals in the multi-seconds range. We have found that both cortical and striatal firing rates contain information that the rat can use to identify how much time has elapsed both from trial onset and from the onset of an active response state. I describe findings showing that the striatal neurons that are modulated by time are also modulated by overt behaviors, suggesting that time modulates the strength of motor coding in the striatum, rather than being represented as an abstract quantity in isolation. I also describe work showing that there are a variety of temporally informative activity patterns in pre-motor cortex, and argue that the heterogeneity of these patterns can enhance an organism's temporal estimate. Finally, I describe recent behavioral work from my lab in which the simultaneous cueing of multiple durations leads to a scalar temporal expectation at an intermediate time, providing strong support for a monotonic representation of time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.