Evidence map›Paper›PMID 25356601›Full record

ArticleJAMA otolaryngology-- head & neck surgery2015

Systemwide change of sedation wean protocol following pediatric laryngotracheal reconstruction.

Elliott D Kozin, Brian M Cummings, Derek J Rogers, Brian Lin, Rosh Sethi, Natan Noviski, Christopher J Hartnick

Abstract readEvaluation Study
In one paragraph

Article in JAMA otolaryngology-- head & neck surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Guideline
  2. [Clinical practice guidelines for pediatric open laryngotracheoplasty(2026)].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026
    Guideline
  3. Article
  4. Exposure-Based Methadone and Lorazepam Weaning Protocol Reduces Wean Length in Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elliott D KozinDepartment of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts2Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston.
Brian M CummingsDepartment of Pediatrics, Massachusetts General Hospital, Boston.
Derek J RogersDepartment of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts2Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston.
Brian LinDepartment of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts2Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston.
Rosh SethiDepartment of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts.
Natan NoviskiDepartment of Pediatrics, Massachusetts General Hospital, Boston.
Christopher J HartnickDepartment of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts2Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Boston.
Harvard University · USMassachusetts Eye and Ear Infirmary · USMassachusetts General Hospital · US

Funding

RESEARCH TRAINING IN OTOLARYNGOLOGYT32DC000020 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI JUNG, DAVID H, SIMONYAN, KRISTINA · 1990 to 2025
$2.4M
NIDCD NIH HHS T32 DC000020
6 · The paper itself

Abstract

importancePediatric laryngotracheal reconstruction (LTR) remains the standard surgical technique for expanding a stenotic airway and necessitates a multidisciplinary team. Sedation wean following LTR is a critical component of perioperative care. We identified variation and communications deficiencies with our sedation wean practice and describe our experience implementing a standardized sedation wean protocol.

objectiveTo standardize and decrease length of sedation wean in pediatric patients undergoing LTR. DESIGN, SETTING, AND

participantsUsing Institute for Healthcare Improvement (IHI) methodology, we implemented systemwide change at a tertiary care center with the goal of improving care based on best practice guidelines. We created a standardized electronic sedation wean communication document and retrospectively examined our experience in 29 consecutive patients who underwent LTR before (n = 16, prewean group) and after (n = 13, postwean group) wean document implementation.

interventionsImplementation of a standardized sedation protocol. MAIN OUTCOMES AND MEASURES: Presence of sedation wean document in the electronic medical record, length of sedation wean, and need for continued wean after discharge.

resultsThe sedation wean document was used in 92.3% patients in the postwean group. With the new process, the mean (SD) length of sedation wean was reduced from 16.19 (11.56) days in the prewean group to 8.92 (3.37) days in the postwean group (P = .045). Fewer patients in the postwean group required continued wean after discharge (81.3% vs 33.3%; P = .02). CONCLUSIONS AND RELEVANCE: We implemented a systemwide process change with the goal of improving care based on best practice guidelines, which significantly decreased the time required for sedation wean following LTR. Our methodological approach may have implications for other heterogeneous patient populations requiring a sedation wean.

Indexed as

Child, PreschoolDeep SedationFemaleHumansInfantLaryngostenosisMalePlastic Surgery ProceduresTreatment Outcome

Identifiers

PMID25356601
PMCPMC4465249
OpenAlexW1972931436

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.