Trial reportPloS one2014
Changes in outer retinal microstructures during six month period in eyes with acute zonal occult outer retinopathy-complex.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Differential diagnosis and clinical predictors in suspected optic neuritis.Japanese journal of ophthalmology · 2026Article
- Characterization of the Subclinical Perilesional Zone in the Macula of Early-Stage ABCA4 Disease.Translational vision science & technology · 2025Article
- A systematic review of acute zonal occult outer retinopathy with a focus on attempted treatment modalities.Current ophthalmology reports · 2022Article
- Classification of good visual acuity over time in patients with branch retinal vein occlusion with macular edema using support vector machine.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- An update on autoimmune retinopathy.Indian journal of ophthalmology · 2020Review
- RDH5-Related Fundus Albipunctatus in a Large Japanese Cohort.Investigative ophthalmology & visual science · 2020Article
- Non-paraneoplastic autoimmune retinopathy: multimodal testing characteristics of 13 cases.Journal of ophthalmic inflammation and infection · 2019Article
- New clinical ultrahigh-resolution SD-OCT using A-scan matching algorithm.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- The clinical characteristics and prognosis of acute zonal occult outer retinopathy.International ophthalmology · 2018Observational
- Acute Zonal Cone Photoreceptor Outer Segment Loss.JAMA ophthalmology · 2017Article
- Objective Analysis of Hyperreflective Outer Retinal Bands Imaged by Optical Coherence Tomography in Patients With Stargardt Disease.Investigative ophthalmology & visual science · 2015Article
- Usefulness of Color Laser Scanning Ophthalmoscopy and Optical Coherence Tomography Angiography in the Diagnosis of Acute Zonal Occult Outer Retinopathy Complex: A Report of Two Cases.Case reports in ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo study the changes in the outer retinal microstructures during a six month period after the onset of acute zonal occult outer retinopathy (AZOOR)-complex by spectral-domain optical coherence tomography (SD-OCT).
methodsSeventeen eyes of 17 patients with the AZOOR-complex were studied. The integrity of the external limiting membrane (ELM), ellipsoid zone (EZ; also called the inner/outer segment junction), and interdigitation zone (IDZ; also called the cone outer segment tips) were evaluated in the SD-OCT images obtained at the initial visit and at six months. The three highly reflective bands were divided into three types; continuous, discontinuous, and absent. The integrity of the outer nuclear layer (ONL) was also assessed.
resultsAmong the three highly reflective bands, the IDZ was most altered at the initial visit and least recovered at six months. Fifteen of 17 eyes (88%) had a recovery of at least one of the three bands at six months in the retinal area where the ONL was intact, and these areas showed an improvement of visual field. Three eyes (18%) had retinal areas where the ONL was absent at the initial visit, and there was no recovery in both the retinal structures and visual fields in these areas.
conclusionsOur results indicate that more than 85% eyes with AZOOR-complex show some recovery in the microstructures of the outer retina during a six month period if the ONL is intact. We conclude that SD-OCT is a useful method to monitor the changes of the outer retinal microstructure in eyes with the AZOOR-complex.
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