ArticleAnnals of clinical and translational neurology2014
Novel features of early burst suppression predict outcome after birth asphyxia.
Article in Annals of clinical and translational neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Pooled it
- The SafeBoosC II randomized trial: treatment guided by near-infrared spectroscopy reduces cerebral hypoxia without changing early biomarkers of brain injury.Pediatric research · 2016Trial
- Continuous EEG monitoring after neonatal cardiac surgery: seizure incidence and prognostic background abnormalities.Pediatric research · 2026Article
- Quantitative EEG features during the first day correlate to clinical outcome in perinatal asphyxia.Pediatric research · 2025Article
- Review
- Early EEG-burst sharpness and 2-year disability in extremely preterm infants.Pediatric research · 2024Article
- Article
- Prognostic value of neonatal EEG following therapeutic hypothermia in survivors of hypoxic-ischemic encephalopathy.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- Gabaergic Interneurons in Early Brain Development: Conducting and Orchestrated by Cortical Network Activity.Frontiers in molecular neuroscience · 2021Article
- Automated cot-side tracking of functional brain age in preterm infants.Annals of clinical and translational neurology · 2020Article
- Stability of neuronal avalanches and long-range temporal correlations during the first year of life in human infants.Brain structure & function · 2020Article
- Measuring Cot-Side the Effects of Parenteral Nutrition on Preterm Cortical Function.Frontiers in human neuroscience · 2020Article
- Automated EEG background analysis to identify neonates with hypoxic-ischemic encephalopathy treated with hypothermia at risk for adverse outcome: A pilot study.Pediatrics and neonatology · 2019Article
- Electroencephalographic features of discontinuous activity in anesthetized infants and children.PloS one · 2019Article
- Thalamus Controls Development and Expression of Arousal States in Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Hemodynamic response to burst-suppressed and discontinuous electroencephalography activity in infants with hypoxic ischemic encephalopathy.Neurophotonics · 2016Article
- Objective differentiation of neonatal EEG background grades using detrended fluctuation analysis.Frontiers in human neuroscience · 2015Article
- Scale-free bursting in human cortex following hypoxia at birth.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Critical role for resource constraints in neural models.Frontiers in systems neuroscience · 2014Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Burst suppression patterns in the electroencephalogram are a reliable marker of recent severe brain insult. Here we analyze statistical properties of bursts occurring in 20 electroencephalographic recordings acquired from hypothermic asphyxic newborns in the hours immediately following birth. We show that the distributions of burst area and duration in these acute data predict later clinical outcome in both structural neuroimaging and neurodevelopment. Our findings indicate the first early electroencephalographic metrics that offer outcome prediction in asphyxic neonates undergoing hypothermia treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.