Evidence map›Paper›PMID 25356384›Full record

ArticleAnnals of clinical and translational neurology2014

Motor threshold predicts working memory performance in healthy humans.

Nathalie Schicktanz, Kyrill Schwegler, Matthias Fastenrath, Klara Spalek, Annette Milnik, Andreas Papassotiropoulos, Thomas Nyffeler, Dominique J-F de Quervain

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Article in Annals of clinical and translational neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathalie SchicktanzDivision of Cognitive Neuroscience, Department of Psychology, University of Basel Basel, Switzerland ; Psychiatric University Clinics, University of Basel Basel, Switzerland.
Kyrill SchweglerDivision of Cognitive Neuroscience, Department of Psychology, University of Basel Basel, Switzerland ; Psychiatric University Clinics, University of Basel Basel, Switzerland.
Matthias FastenrathDivision of Cognitive Neuroscience, Department of Psychology, University of Basel Basel, Switzerland.
Klara SpalekDivision of Cognitive Neuroscience, Department of Psychology, University of Basel Basel, Switzerland.
Annette MilnikDivision of Molecular Neuroscience, Department of Psychology, University of Basel Basel, Switzerland.
Andreas PapassotiropoulosPsychiatric University Clinics, University of Basel Basel, Switzerland ; Division of Molecular Neuroscience, Department of Psychology, University of Basel Basel, Switzerland ; Life Sciences Training Facility, Department Biozentrum, University of Basel Basel, Switzerland.
Thomas NyffelerDepartments of Neurology and Clinical Research, Perception and Eye Movement Laboratory Inselspital, Bern University Hospital, University of Bern Bern, Switzerland ; Center of Neurology and Neurorehabilitation, Luzerner Kantonsspital Luzern, Switzerland.
Dominique J-F de QuervainDivision of Cognitive Neuroscience, Department of Psychology, University of Basel Basel, Switzerland ; Psychiatric University Clinics, University of Basel Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive functions, such as working memory, depend on neuronal excitability in a distributed network of cortical regions. It is not known, however, if interindividual differences in cortical excitability are related to differences in working memory performance. In the present transcranial magnetic stimulation study, which included 188 healthy young subjects, we show that participants with lower resting motor threshold, which is related to higher corticospinal excitability, had increased 2-back working memory performance. The findings may help to better understand the link between cortical excitability and cognitive functions and may also have important clinical implications with regard to conditions of altered cortical excitability.

Identifiers

PMID25356384
PMCPMC4207507

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.