ArticleInternational journal of clinical and experimental medicine2014
Prognostic and clinicopathological differences of DcR3 in gastrointestinal cancer: evidence from meta-analysis.
Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Decoy Receptor 3 (DcR3) as a Biomarker of Tumor Deterioration in Female Reproductive Cancers: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2016Pooled it
- DcR3-associated risk score: correlating better prognosis and enhanced predictive power in colorectal cancer.Discover oncology · 2024Article
- DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway.OncoTargets and therapy · 2018Article
- Decoy receptor 3: an endogenous immunomodulator in cancer growth and inflammatory reactions.Journal of biomedical science · 2017Review
- Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis.OncoTargets and therapy · 2017Article
- A functional polymorphism rs2257440 in the geneInternational journal of clinical and experimental pathology · 2017Article
- Idiopathic pulmonary fibrosis fibroblasts become resistant to Fas ligand-dependent apoptosis via the alteration of decoy receptor 3.The Journal of pathology · 2016Article
- [Cell death in malignant tumors. Relevance of cell death regulation for metastasis].Der Pathologe · 2015Review
- The Role of Decoy Receptor DcR3 in Gastrointestinal Malignancy.Cancer diagnosis & prognosisReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many studies reported that DcR3 participated in the clinicopathological characteristics of gastrointestinal cancer, however, they all included few patients and had inconsistent results. So we conducted a meta-analysis to explore the correlation between overexpression of DcR3 and the clinicopathological characteristics of gastrointestinal cancer. Identical search strategies were used to search relevant literatures in PubMed, Web of Science and Chinese Biomedical Literature Database. The prognostic significances and clinicopathological differences of DcR3 in gastrointestinal cancer were analyzed. A total of 28 studies comprising 3294 gastrointestinal cancer patients met the inclusion criteria. Overexpression of DcR3 was closely related with these clinicopathological features, including TNM stages (OR = 1.63, 95% CI 1.35-1.98), grade of differentiation (OR = 1.31, 95% CI 1.10-1.56), lymph node metastasis (OR = 2.02, 95% CI 1.66-2.47), infiltration degree (OR = 1.72, 95% CI 1.38-2.12), and metastasis (OR = 1.66, 95% CI 1.27-2.16). DcR3 may play an important role in gastrointestinal cancer, and DcR3 indicated distinct clinicopathologic features.
Indexed as
Identifiers
25356187PMC4211837W2364443457What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.