Evidence map›Paper›PMID 25356138›Full record

ArticleInternational journal of clinical and experimental medicine2014

Surgical management of cervical esophageal carcinoma with larynx preservation and reconstruction.

Fenglin Sun, Xuezhong Li, Dapeng Lei, Tong Jin, Dayu Liu, Hui Zhao, Qiuan Yang, Guojun Li, Xinliang Pan

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Challenging esophageal surgery: risk factors, outcomes, and a comparative single-center analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  4. Review
  5. Article
  6. Real-world treatment patterns and outcomes in Japanese patients with cervical esophageal cancer.Esophagus : official journal of the Japan Esophageal Society · 2022
    Article
  7. Article
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  16. Management algorithm for failed gastric pull up reconstruction of laryngopharyngectomy defects: case report and review of the literature.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2016
    Review
  17. Article
  18. Therapeutic effects of cytoprotective agent on breast reconstruction after breast cancer surgery.International journal of clinical and experimental medicine · 2015
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Fenglin SunDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China ; Department of Otorhinolaryngology, Central Hospital of Zibo Shandong Province, P. R. China.
Xuezhong LiDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China.
Dapeng LeiDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China.
Tong JinDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China.
Dayu LiuDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China.
Hui ZhaoDepartment of Thoracic Surgery, Qilu Hospital, Shandong University P. R. China.
Qiuan YangDepartment of Radiation, Oncology Center, Qilu Hospital of Shandong University Jinan 250012, Shandong, P. R. China.
Guojun LiDepartment of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center Houston, TX 77030, USA.
Xinliang PanDepartment of Otorhinolaryngology, Qilu Hospital, Shandong University, Key Laboratory of Otolaryngology, Ministry of Health Jinan 250012, Shandong, P. R. China.
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere is no generally accepted treatment strategy for cervical esophageal carcinoma. The purpose of this study was to evaluate the operative outcomes of reconstruction after resection of cervical esophageal and hypopharynx-esophagus junction carcinoma with larynx preservation.

methodsWe retrospectively reviewed the data of 79 patients with carcinoma of the hypopharynx-esophagus junction and cervical esophagus. Transhiatal total esophagectomy without thoracotomy was carried out in 67 patients who underwent gastric pull-up (GP) or colon interposition (CI) techniques. Transcervical limited pharyngo-cervical esophagectomy was performed in the patients with the pectoralis major flap alone or combined with the split graft (PMF/CWSG) for reconstruction. Seventy-two patients received postoperative adjuvant therapy.

resultsThe 3-year and 5-year overall survival rates were 66.4% and 45.5%, respectively. The average time to resumption of oral feeding was 25.2 days. All patients had preserved laryngeal function. The overall incidence of complications was 29.1% (23/79), which included cervical fistula, abdominal wound dehiscence, liquefaction necrosis of abdominal fat, and pleural effusion.

conclusionsSurgical resection of cervical esophageal carcinoma and laryngeal preservation is possible. Complete esophagectomy should be performed when the resection extends below the thoracic inlet. The reconstruction methods we performed were safe and effective for the immediate restoration of alimentary continuity after resection of cervical esophageal and pharyngo-cervical esophageal carcinoma; and the patients with PMF/CWSG reconstruction had a better survival than those with GP or CI reconstruction. Combined with radiotherapy, the resectability rate and survival rate of cervical esophageal carcinoma can be improved.

Indexed as

Carcinomacervical esophaguscolon interpositiongastric pull-uplarynx preservationoral cancer

Identifiers

PMID25356138
PMCPMC4211788
OpenAlexW2180166158

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.