Evidence map›Paper›PMID 25356036›Full record

ReviewWorld journal of gastroenterology2014

Adjuvant therapy in pancreatic cancer.

Owain Peris Jones, James Daniel Melling, Paula Ghaneh

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Functional genetic variants ofJournal of Cancer · 2020
    Article
  7. Article
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  11. Identification of Sox6 as a regulator of pancreatic cancer development.Journal of cellular and molecular medicine · 2018
    Article
  12. Article
  13. Article
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  16. Article
  17. Article
  18. Article
  19. Pancreatic cancer incidence and mortality patterns in China, 2011.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Owain Peris JonesOwain Peris Jones, James Daniel Melling, Paula Ghaneh, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, 5 Floor UCD Building, Daulby Street, Liverpool L69 3GA, United Kingdom.
James Daniel MellingOwain Peris Jones, James Daniel Melling, Paula Ghaneh, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, 5 Floor UCD Building, Daulby Street, Liverpool L69 3GA, United Kingdom.
Paula GhanehOwain Peris Jones, James Daniel Melling, Paula Ghaneh, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, 5 Floor UCD Building, Daulby Street, Liverpool L69 3GA, United Kingdom.

Funding

Cancer Research UK 11883Cancer Research UK 15957Cancer Research UK 16186Cancer Research UK 16812Cancer Research UK 17680Cancer Research UK 8968Department of Health 08/29/02
6 · The paper itself

Abstract

Pancreatic cancer remains one of the leading causes of cancer related death worldwide with an overall five-year survival of less than 5%. Potentially curative surgery, which alone can improve 5-year survival to 10%, is an option for only 10%-20% of patients at presentation owing to local invasion of the tumour or metastatic disease. Adjuvant chemotherapy has been shown to improve 5-year survival to 20%-25% but conflicting evidence remains with regards to chemoradiation. In this article we review the current evidence available from published randomised trials and discuss ongoing phase III trials in relation to adjuvant therapy in pancreatic cancer.

Indexed as

Carcinoma, Pancreatic DuctalChemoradiotherapy, AdjuvantChemotherapy, AdjuvantClinical Trials, Phase III as TopicEvidence-Based MedicineHumansNeoplasm StagingPancreatic NeoplasmsTreatment OutcomeAdjuvantChemoradiotherapyChemotherapyGemcitabinePancreatic cancerPhase III

Identifiers

PMID25356036
PMCPMC4209539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.