Evidence map›Paper›PMID 25356021›Full record

ReviewWorld journal of gastroenterology2014

Non-invasive assessment of liver fibrosis in chronic hepatitis B.

Federica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Pietro Lampertico, Dario Conte, Mirella Fraquelli

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. [Clinical value of multiparameteric quantitative ultrasound for assessing high-risk steatohepatitis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  3. Article
  4. Serum/Plasma Proteome in Non-Malignant Liver Disease.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Noninvasive Evaluation of Liver Fibrosis in a Sample of Putative Inactive HBV Carriers in Rome, Italy.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021
    Article
  10. Limitations of non-invasive tests for assessment of liver fibrosis.JHEP reports : innovation in hepatology · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Hepatitis C Treatment and Barriers to Eradication.Clinical and translational gastroenterology · 2016
    Article
  18. Observational
  19. Natural regression of fibrosis in chronic hepatitis B.World journal of gastroenterology · 2016
    Review
  20. [Comparison of FibroTouch and acoustic radiation force impulse in diagnosis of liver fibrosis in patients with chronic hepatitis B].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Federica BranchiFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Clara Benedetta ContiFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Alessandra BaccarinFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Pietro LamperticoFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Dario ConteFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.
Mirella FraquelliFederica Branchi, Clara Benedetta Conti, Alessandra Baccarin, Dario Conte, Mirella Fraquelli, Second Division of Gastroenterology, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, 20122 Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The goal of this review is to provide a comprehensive picture of the role, clinical applications and future perspectives of the most widely used non-invasive techniques for the evaluation of hepatitis B virus (HBV) infection. During the past decade many non-invasive methods have been developed to reduce the need for liver biopsy in staging fibrosis and to overcome whenever possible its limitations, mainly: invasiveness, costs, low reproducibility, poor acceptance by patients. Elastographic techniques conceived to assess liver stiffness, in particular transient elastography, and the most commonly used biological markers will be assessed against their respective role and limitations in staging hepatic fibrosis. Recent evidence highlights that both liver stiffness and some bio-chemical markers correlate with survival and major clinical end-points such as liver decompensation, development of hepatocellular carcinoma and portal hypertension. Thus the non-invasive techniques here discussed can play a major role in the management of patients with chronic HBV-related hepatitis. Given their prognostic value, transient elastography and some bio-chemical markers can be used to better categorize patients with advanced fibrosis and cirrhosis and assign them to different classes of risk for clinically relevant outcomes. Very recent data indicates that the combined measurements of liver and spleen stiffness enable the reliable prediction of portal hypertension and esophageal varices development.

Indexed as

Elasticity Imaging TechniquesLiverBiomarkersDisease ProgressionEsophageal and Gastric VaricesHepatitis B, ChronicHumansHypertension, PortalLiver CirrhosisPredictive Value of TestsPrognosisReproducibility of ResultsRisk FactorsSeverity of Illness IndexBiomarkersCirrhosisHepatitis B virusLiver fibrosisNon invasive markersTransient elastography

Identifiers

PMID25356021
PMCPMC4209524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.