Evidence map›Paper›PMID 25356018›Full record

SynthesisWorld journal of gastroenterology2014

Evidence-based assessment of proton-pump inhibitors in Helicobacter pylori eradication: a systematic review.

Vinayak Nagaraja, Guy D Eslick

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Efficiency and Mechanism Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  4. Article
  5. Clinical experience of use ofPrzeglad gastroenterologiczny · 2020
    Article
  6. Antibiotic treatment for Helicobacter pylori: Is the end coming?World journal of gastrointestinal pharmacology and therapeutics · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Vinayak NagarajaVinayak Nagaraja, Guy D Eslick, The Whiteley-Martin Research Centre, Discipline of Surgery, The University of Sydney, Nepean Hospital, Penrith, NSW 2751, Australia.
Guy D EslickVinayak Nagaraja, Guy D Eslick, The Whiteley-Martin Research Centre, Discipline of Surgery, The University of Sydney, Nepean Hospital, Penrith, NSW 2751, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptic ulcer disease continues to be issue especially due to its high prevalence in the developing world. Helicobacter pylori (H. pylori) infection associated duodenal ulcers should undergo eradication therapy. There are many regimens offered for H. pylori eradication which include triple, quadruple, or sequential therapy regimens. The central aim of this systematic review is to evaluate the evidence for H. pylori therapy from a meta-analytical outlook. The consequence of the dose, type of proton-pump inhibitor, and the length of the treatment will be debated. The most important risk factor for eradication failure is resistance to clarithromycin and metronidazole.

Indexed as

Anti-Bacterial AgentsChi-Square DistributionDrug Administration ScheduleDrug Resistance, BacterialDrug Therapy, CombinationHelicobacter InfectionsHelicobacter pyloriHumansOdds RatioPeptic UlcerProton Pump InhibitorsRisk FactorsTreatment OutcomeAnti-Bacterial AgentsProton Pump InhibitorsHelicobacter pyloriPeptic ulcer diseaseProton-pump inhibitorsSystematic review

Identifiers

PMID25356018
PMCPMC4209521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.