ArticlePublic health nutrition2015
Associations of serum 25-hydroxycholecalciferol and parathyroid hormone with serum lipids differ by sex and vitamin D status.
Article in Public health nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Association between vitamin D deficiency and serum lipid levels in a group of Romanian patients.Medicine and pharmacy reports · 2024Article
- Association of 25-hydroxyvitamin D levels with lipid profiles in osteoporosis patients: a retrospective cross-sectional study.Journal of orthopaedic surgery and research · 2023Article
- The Relationship of 25(OH)DMedicina (Kaunas, Lithuania) · 2022Article
- Article
- The association between serum 25-hydroxyvitamin D concentrations and serum lipids in the Southern Thai population.Archives of medical science : AMS · 2022Article
- Article
- Association between standardized vitamin 25(OH)D and dyslipidemia: a community-based study in Riyadh, Saudi Arabia.Environmental health and preventive medicine · 2020Article
- The association between serum 25-hydroxyvitamin D3 concentration and serum lipids in the rural population of China.Lipids in health and disease · 2017Article
- Effect of waist circumference on the association between serum 25-hydroxyvitamin D and serum lipids: results from the National Health and Nutrition Examination Survey 2001-2006.Public health nutrition · 2017Article
- The Associations of Serum Lipids with Vitamin D Status.PloS one · 2016Article
- The interaction effects of aerobic exercise training and vitamin D supplementation on plasma lipid profiles and insulin resistance in ovariectomized rats.Journal of exercise nutrition & biochemistry · 2015Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAlthough emerging evidence indicates an association between vitamin D and serum lipids, the data are still inconsistent. The purpose of the present study was to investigate whether 25-hydroxycholecalciferol (25-hydroxyvitamin D3; 25(OH)D3) or intact parathyroid hormone (iPTH) was independently related to serum lipids in elderly women and men.
designCross-sectional study. Fasting serum levels of 25(OH)D3, iPTH, TAG, total cholesterol (TC), HDL cholesterol (HDL-C) and LDL cholesterol (LDL-C) were assessed. Body composition was measured by bioelectrical impedance analysis. Lifestyle factors, such as nutrient intake, time spent outdoors, physical activity, smoking, supplement intake and medication, were assessed by questionnaires. Multiple regression analyses were performed to examine associations of 25(OH)D3 and iPTH with serum lipids.
settingGiessen, Germany. SUBJECTS: One hundred and ninety-three well-functioning German elderly aged 66-96 years.
resultsAfter adjusting for age, body fat, physical activity, smoking, alcohol intake, lipid-modifying drugs and either iPTH or 25(OH)D3, 25(OH)D3 was a predictor of TAG (standardised coefficient beta (β)=-0.180), HDL-C (β=0.197), LDL-C:HDL-C (β=-0.298) and TC:HDL-C (β=-0.302) in women, whereas iPTH was a predictor of HDL-C (β=-0.297) in men. In sub-analysis, associations between 25(OH)D3 and TC (β=-0.252), HDL-C (β=0.230), LDL-C (β=-0.324), LDL-C:HDL-C (β=-0.412) and TC:HDL-C (β=-0.380) were found in women with 25(OH)D3 concentrations above or equal the median vitamin D status (62.3 nmol/l), but not in women with lower 25(OH)D3 concentrations.
conclusionsIn the elderly, associations of 25(OH)D3 and iPTH with serum lipids may differ by sex and may require a vitamin D status above 62 nmol/l.
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