ArticlePediatric nephrology (Berlin, Germany)2015
Left ventricular mass and diastolic function in obese children and adolescents.
Article in Pediatric nephrology (Berlin, Germany), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- The effect of overweight/obesity on diastolic function in children and adolescents: A meta-analysis.Clinical obesity · 2021Pooled it
- Childhood Obesity and Congenital Heart Disease: A Lifelong Struggle.Journal of clinical medicine · 2023Review
- 24-Hour ambulatory blood pressure monitoring 7 years after intensive care unit admission.Pediatric nephrology (Berlin, Germany) · 2022Article
- Left Ventricular Diastolic Dysfunction Among Youth with Obesity and History of Elevated Blood Pressure.The Journal of pediatrics · 2021Article
- The impact of obesity on left ventricular hypertrophy and diastolic dysfunction in children and adolescents.Scientific reports · 2021Article
- Racial differences of early vascular aging in children and adolescents.Pediatric nephrology (Berlin, Germany) · 2021Review
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth With Elevated Blood Pressure.Hypertension (Dallas, Tex. : 1979) · 2020Article
- Different Patterns of Left Ventricular Hypertrophy in Metabolically Healthy and Insulin-Resistant Obese Subjects.Nutrients · 2020Article
- OSA and Cardiovascular Risk in Pediatrics.Chest · 2019Review
- Impact of Obesity on Left Ventricular Thickness in Children with Hypertrophic Cardiomyopathy.Pediatric cardiology · 2019Article
- Cardiac function in adolescents with obesity: cardiometabolic risk factors and impact on physical fitness.International journal of obesity (2005) · 2019Observational
- Serum apoptotic marker M30 is positively correlated with early diastolic dysfunction in adolescent obesity.PloS one · 2019Article
- Fibroblast growth factor-23 is independently associated with cardiac mass in African-American adolescent males.Journal of the American Society of Hypertension : JASH · 2017Article
- The Role of Obesity in the Development of Left Ventricular Hypertrophy Among Children and Adolescents.Current hypertension reports · 2016Review
- Evaluating the benefits of home-based management of atrial fibrillation: current perspectives.Pragmatic and observational research · 2016Review
- Left ventricular hypertrophy and diastolic function in children and adolescents with essential hypertension.Clinical hypertension · 2015Article
- Determinants of Left Ventricular Mass Among Apparently Normal Children in Enugu State.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
- The analgesic effects of botulinum neurotoxin by modulating pain-related receptors; A literature review.Molecular painReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur aims were to assess left ventricular structure and diastolic function in obese subjects stratified according to ambulatory blood pressure status, and to investigate independent predictors of the left ventricular mass (LVM) index.
methodsObese subjects aged 9-19 years referred for ambulatory blood pressure monitoring (ABPM) were evaluated in the cross-sectional study. In addition to biochemical and anthropometric measurements, subjects underwent ABPM, Doppler echocardiography, and treadmill exercise test.
resultsAccording to ABPM results, 103 subjects with obesity (mean age 14.1 ± 2 years) were split in two groups: 49 hypertensive, and 54 without hypertension. Left ventricular hypertrophy was found in 16.3 % of hypertensive, and 5.6 % of normotensive. Variables included in stepwise regression analysis as potential determinants of LVM index were age, body mass index z score, waist circumference, peak systolic blood pressure on exercise test, 24-h heart rate, and night heart rate. Peak systolic blood pressure (adjusted R(2) = 0.051, β = 0.245, p = 0.013) remained as the independent predictor of LVM index. Diastolic function evaluated by mitral E/A ratio was decreased in both obese groups.
conclusionsEarly markers of cardiac disease including hypertrophy and diastolic dysfunction of the left ventricle are present in youths with obesity prior to the development of sustained hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.