ReviewThrombosis and haemostasis2015
Selenoproteins and cardiovascular stress.
Review in Thrombosis and haemostasis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Selenium nutritional status and cardiovascular diseases: mechanisms of cardioprotection and 21 years of global research trends in precision prevention (2005-2026).Frontiers in nutrition · 2026Pooled it
- Involvement of heat shock proteins HSP70 in the mechanisms of endogenous neuroprotection: the prospect of using HSP70 modulators.Frontiers in cellular neuroscience · 2023Pooled it
- Glycemic and lipid responses to selenium-enriched vs. zeaxanthin-enriched eggs in patients with type 2 diabetes: a 12-week randomized controlled trial.Frontiers in nutrition · 2026Trial
- Multi-omics data mining combined with experimental validation reveals ferroptosis- and autophagy-associated hub genes as diagnostic candidates and immune modulators in atherosclerosis.Animal models and experimental medicine · 2026Article
- 3S-DB identifies an RNA repository facilitating stop codon readthrough for selenocysteine insertion and selenoproteome expansion.Redox biology · 2025Article
- DeepSecMS Advances DIA-Based Selenoproteome Profiling Through Cys-to-Sec Proxy Training.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The bidirectional regulatory effect of TXNRD2 methylation in patients with chronic heart failure and its nonlinear dose-response relationship with key clinical parameters.Journal of cardiothoracic surgery · 2025Article
- Essential and Non-Essential Metals and Metalloids and Their Role in Atherosclerosis.Cardiovascular toxicology · 2025Review
- Unveiling the Metabolic Trajectory of Pig Feces Across Different Ages and Senescence.Metabolites · 2024Article
- N-Stearoylethanolamine Exerts Cardioprotective Effects in Old Rats.Current aging science · 2024Article
- Impact of dietary selenium and blood concentration on liver function: a population-based study.Frontiers in nutrition · 2024Article
- Association between methionine sulfoxide and risk of moyamoya disease.Frontiers in neuroscience · 2023Article
- Multivitamin/mineral supplementation and the risk of cardiovascular disease: a large prospective study using UK Biobank data.European journal of nutrition · 2022Article
- The molecular regulation of autophagy in antimicrobial immunity.Journal of molecular cell biology · 2022Article
- The Role and Mechanism of Essential Selenoproteins for Homeostasis.Antioxidants (Basel, Switzerland) · 2022Review
- Effects of exogenous sucrose and selenium on plant growth, quality, and sugar metabolism of pea sprouts.Journal of the science of food and agriculture · 2022Article
- Dissecting the cellular landscape and transcriptome network in viral myocarditis by single-cell RNA sequencing.iScience · 2022Article
- The Role of Selenoprotein Tissue Homeostasis in MetS Programming: Energy Balance and Cardiometabolic Implications.Antioxidants (Basel, Switzerland) · 2022Review
- Serum Zinc and Selenium Concentrations in Patients with Hypertrophy and Remodelling of the Left Ventricle Secondary to Arterial Hypertension.Antioxidants (Basel, Switzerland) · 2021Article
- The Impact of Selenium Deficiency on Cardiovascular Function.International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Dietary selenium (Se) is an essential micronutrient that exerts its biological effects through its incorporation into selenoproteins. This family of proteins contains several antioxidant enzymes such as the glutathione peroxidases, redox-regulating enzymes such as thioredoxin reductases, a methionine sulfoxide reductase, and others. In this review, we summarise the current understanding of the roles these selenoproteins play in protecting the cardiovascular system from different types of stress including ischaemia-reperfusion, homocysteine dysregulation, myocardial hypertrophy, doxirubicin toxicity, Keshan disease, and others.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.