ReviewNutrients2014
The influence of early life nutrition on epigenetic regulatory mechanisms of the immune system.
Review in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 75 citations in OpenAlex.
- Epigenome-Wide Association of Infant Feeding and Changes in DNA Methylation from Birth to 10 Years.Nutrients · 2020Trial
- Randomized controlled trial on the influence of dietary intervention on epigenetic mechanisms in children with cow's milk allergy: the EPICMA study.Scientific reports · 2019Trial
- Article
- Human milkFrontiers in nutrition · 2025Review
- Food Allergy-Related Bullying in Pediatric Patients: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- DNA methylation in necrotizing enterocolitis.Expert reviews in molecular medicine · 2024Review
- A review of current evidence on food allergies during pregnancy.Food science & nutrition · 2023Review
- Nutrition and Immunity in Perinatal Hypoxic-Ischemic Injury.Nutrients · 2022Review
- Nutrition during Pregnancy and Lactation: Epigenetic Effects on Infants' Immune System in Food Allergy.Nutrients · 2022Review
- "GENYAL" Study to Childhood Obesity Prevention: Methodology and Preliminary Results.Frontiers in nutrition · 2022Article
- Epigenetics in Food Allergy and Immunomodulation.Nutrients · 2021Review
- Article
- Dysbiosis in the Development of Type I Diabetes and Associated Complications: From Mechanisms to Targeted Gut Microbes Manipulation Therapies.International journal of molecular sciences · 2021Review
- Expression Changes in Epigenetic Gene Pathways Associated With One-Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non-Typical Neurodevelopment.Autism research : official journal of the International Society for Autism Research · 2021Article
- Nutrigenomics in Regulating the Expression of Genes Related to Type 2 Diabetes Mellitus.Frontiers in physiology · 2021Review
- The microbiome and its impact on food allergy and atopic dermatitis in children.Postepy dermatologii i alergologii · 2020Review
- Article
- The Impact of Milk and Its Components on Epigenetic Programming of Immune Function in Early Life and Beyond: Implications for Allergy and Asthma.Frontiers in immunology · 2020Review
- DNA Methylation Signatures of Breastfeeding in Buccal Cells Collected in Mid-Childhood.Nutrients · 2019Article
- Regulation of rumen development in neonatal ruminants through microbial metagenomes and host transcriptomes.Genome biology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immune system is exquisitely sensitive to environmental changes. Diet constitutes one of the major environmental factors that exerts a profound effect on immune system development and function. Epigenetics is the study of mitotically heritable, yet potentially reversible, molecular modifications to DNA and chromatin without alteration to the underlying DNA sequence. Nutriepigenomics is an emerging discipline examining the role of dietary influences on gene expression. There is increasing evidence that the epigenetic mechanisms that regulate gene expression during immune differentiation are directly affected by dietary factors or indirectly through modifications in gut microbiota induced by different dietary habits. Short-chain fatty acids, in particular butyrate, produced by selected bacteria stains within gut microbiota, are crucial players in this network.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.