Evidence map›Paper›PMID 25353660›Full record

SynthesisNutrients2014

Green tea consumption and risk of pancreatic cancer: a meta-analysis.

Jin-Long Zeng, Zhi-Hua Li, Zhi-Chao Wang, Hai-Liang Zhang

Abstract readMeta-Analysis
In one paragraph

Synthesis in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Green tea (Camellia sinensis) for the prevention of cancer.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Polyphenols as Possible Agents for Pancreatic Diseases.Antioxidants (Basel, Switzerland) · 2020
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jin-Long ZengDepartment of Oncology, Zengcheng People's Hospital, Boji Hospital of Sun Yat-sen University, Xingning, 511300, China. zengjinlonger@163.com.
Zhi-Hua LiDepartment of Oncology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510000, China. lizhih@mail.sysu.edu.cn.
Zhi-Chao WangDepartment of Oncology, Zengcheng People's Hospital, Boji Hospital of Sun Yat-sen University, Xingning, 511300, China. wangzc1978@163.com.
Hai-Liang ZhangDepartment of Oncology, Zengcheng People's Hospital, Boji Hospital of Sun Yat-sen University, Xingning, 511300, China. zhanghailiang678@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging laboratory and animal studies indicate that green tea inhibits development and progression of pancreatic cancer, but evidence from epidemiologic studies appears inconsistent and inconclusive. A meta-analysis summarizing published case-control and cohort studies was performed to evaluate the association of green tea consumption with risk of pancreatic cancer. Pertinent studies were identified by a search of PubMed and EMBASE up to April 2014. A random-effects model was assigned to compute summary risk estimates. A total of three case-control studies and five prospective studies were included, comprising 2317 incident cases and 288209 subjects. Of them, three studies were from China and the reminders were conducted in Japan. Overall, neither high vs. low green consumption (odds ratio (OR) = 0.99, 95% confidence interval [CI] = 0.78-1.25), nor an increase in green tea consumption of two cups/day (OR = 0.95, 95% CI = 0.85-1.06) was associated with risk of pancreatic cancer. The null association persisted when the analysis was stratified by sex or restricted to non-smokers. In the stratification by study location, the summary OR for the studies from China and for those from Japan was 0.77 (95% CI = 0.60-0.99) and 1.21 (95% CI = 0.94-1.54), respectively (P for differences = 0.04). Cumulative epidemiologic evidence suggests that green tea consumption is not associated with pancreatic cancer.

Indexed as

Asian PeopleChinaDatabases, FactualDietHumansIncidencePancreatic NeoplasmsRisk FactorsTeaTea

Identifiers

PMID25353660
PMCPMC4245553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.