ArticleFrontiers in public health2014
Association between Vitamin D and Adiponectin and Its Relationship with Body Mass Index: The META-Health Study.
Article in Frontiers in public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Vitamin D-Related Genetic Variations and Nonalcoholic Fatty Liver Disease: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Relationship of maternal obesity and vitamin D concentrations with fetal growth in early pregnancy.European journal of nutrition · 2022Trial
- An Observational Study of the Role of Adiponectin and Vitamin D in Pediatric Asthma and Obesity.Children (Basel, Switzerland) · 2026Article
- Association between Serum Adiponectin and Vitamin D in Obese Pre- and Early Postmenopausal Women: A Cross-Sectional Study.Journal of menopausal medicine · 2026Article
- Enhancing Autologous Fat Graft Retention: The Impact of Inactive Vitamin D3 on Immune Modulation and Extracellular Matrix Remodeling in a Swine Model.Aesthetic surgery journal. Open forum · 2026Article
- Adipose Tissue Dysfunction and Metabolic Diseases: The Role of Vitamin D/Vitamin D Receptor Axis.International journal of molecular sciences · 2025Review
- Association of selected adipokines with vitamin D deficiency in children with inflammatory bowel disease.BMC pediatrics · 2024Article
- The Relationship between Selected Inflammation and Oxidative Stress Biomarkers and Carotid Intima-Media Thickness (IMT) Value in Youth with Type 1 Diabetes Co-Existing with Early Microvascular Complications.Journal of clinical medicine · 2022Article
- Puberty Status Modifies the Effects of Genetic Variants, Lifestyle Factors and Their Interactions on Adiponectin: The BCAMS Study.Frontiers in endocrinology · 2021Article
- Vitamin D deficiency and co-morbidities in COVID-19 patients - A fatal relationship?NFS journal · 2020Article
- The role of vitamin D in obstructive sleep apnoea syndrome.Breathe (Sheffield, England) · 2018Review
- Article
- Better Body Composition and Lipid Profile Can Be Associated with Vitamin D Status in Spanish Elderly? The PHYSMED Study.The journal of nutrition, health & aging · 2017Article
- Results of the META-Health Study Suggest Pathways by Which Vitamin D Affect Obesity and Cardiovascular Risk through Adiponectin Levels may Require Further Characterization in Subgroups.Frontiers in public health · 2014Article
- 25-hydroxyvitamin D levels in patients with obstructive sleep apnea and continuous positive airway pressure treatment: a brief review.Sleep science (Sao Paulo, Brazil)Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundLow vitamin D and adiponectin levels are both associated with obesity and cardiovascular disease. Previous studies have indicated that vitamin D levels are directly associated with adiponectin, and that this association varies across body mass index (BMI) categories; stronger with increasing BMI. Few studies examined this association in African-Americans (AA), known to have lower levels of vitamin D and adiponectin, and in whites.
methodsWe assessed whether serum vitamin D is associated with serum adiponectin in a biracial population-based sample. Cross-sectional analyses were performed on 426 non-diabetic participants (218 whites and 208 AA) from the META-Health Study, a random sample from the metro Atlanta. Age-adjusted correlations and multivariable linear regression were used for analyses. We investigated the effect modification of the BMI categories of lean, overweight, and obese as defined by standard cut-points (25 and 30 kg/m(2)).
resultsThe mean (SD) age of our study sample was 50.5 (9) years. The mean (SD) levels of vitamin D were 27.4 (9.8) ng/mL in white women, 25.5 (9.3) ng/mL in white men, 16.9 (7.3) ng/mL in AA women, and 18.8 (7.3) ng/mL in AA men. The mean (SD) levels of adiponectin were 17.0 (17.1) μg/mL in white women, 9.9 (11.3) μg/mL in white men, 6.6 (4.8) μg/mL in AA women, and 9.4 (11.6) μg/mL in AA men. Among lean white women (n = 63), there was a significant direct association between vitamin D and adiponectin (β = 0.02, p = 0.04) after adjustment for age, systolic blood pressure, HDL-cholesterol, triglycerides, income, and season of blood drawing. On the contrary, in lean AA women (n = 23), there was a significant inverse association (β = -0.06, p = 0.01).
conclusionThe association of vitamin D and adiponectin is dependent on race, gender, and BMI category. Among lean white women, there was a significant direct association, whereas in lean AA women the association was inverse. No association was present among obese individuals.
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