Evidence map›Paper›PMID 25352731›Full record

ArticleBioinformation2014

TargetCompare: A web interface to compare simultaneous miRNAs targets.

Fabiano Cordeiro Moreira, Bruno Dustan, Igor G Hamoy, André M Ribeiro-Dos-Santos, Andrea Ribeiro Dos Santos

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioinformation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. MiRTargetLink--miRNAs, Genes and Interaction Networks.International journal of molecular sciences · 2016
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fabiano Cordeiro MoreiraLaboratorio de Genética Humana e Medica, Instituto de Ciências Biológicas, Universidade Federal do Para, Belem, PA, Brasil ; Centro Universitário do Pará - Área de Ciências Exatas e Tecnologia, , Belém, PA, Brasil.
Bruno DustanLaboratorio de Genética Humana e Medica, Instituto de Ciências Biológicas, Universidade Federal do Para, Belem, PA, Brasil ; Centro Universitário do Pará - Área de Ciências Exatas e Tecnologia, , Belém, PA, Brasil.
Igor G HamoyLaboratorio de Genética Humana e Medica, Instituto de Ciências Biológicas, Universidade Federal do Para, Belem, PA, Brasil ; Universidade Federal Rural da Amazônia, Campus de Capanema, PA, Brasil.
André M Ribeiro-Dos-SantosLaboratorio de Genética Humana e Medica, Instituto de Ciências Biológicas, Universidade Federal do Para, Belem, PA, Brasil.
Andrea Ribeiro Dos SantosLaboratorio de Genética Humana e Medica, Instituto de Ciências Biológicas, Universidade Federal do Para, Belem, PA, Brasil ; Nucleo de Pesquisa em Oncologia, Universidade Federal do Para, Belem, PA, Brasil.
Universidade Federal do Pará · BRUniversidade Federal Rural da Amazônia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledMicroRNAs (miRNAs) are small non-coding nucleotide sequences between 17 and 25 nucleotides in length that primarily function in the regulation of gene expression. A since miRNA has thousand of predict targets in a complex, regulatory cell signaling network. Therefore, it is of interest to study multiple target genes simultaneously. Hence, we describe a web tool (developed using Java programming language and MySQL database server) to analyse multiple targets of pre-selected miRNAs. We cross validated the tool in eight most highly expressed miRNAs in the antrum region of stomach. This helped to identify 43 potential genes that are target of at least six of the referred miRNAs. The developed tool aims to reduce the randomness and increase the chance of selecting strong candidate target genes and miRNAs responsible for playing important roles in the studied tissue. AVAILABILITY: http://lghm.ufpa.br/targetcompare.

Indexed as

BioinformaticsGastric CancermiRNATarget GenesWeb tool

Identifiers

PMID25352731
PMCPMC4209372
OpenAlexW2093481197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.