Evidence map›Paper›PMID 25352566›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2015

Taking advantage of continuity of care documents to populate a research repository.

Jeffrey G Klann, Michael Mendis, Lori C Phillips, Alyssa P Goodson, Beatriz H Rocha, Howard S Goldberg, Nich Wattanasin, Shawn N Murphy

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03911687 (Communicating Narrative Concerns Entered by RNs), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03911687 nacompletednot on this mapstarted 2020, after this paper: background citation

Communicating Narrative Concerns Entered by RNs (CONCERN) Clinical Decision Support (CDS) System

TypeinterventionalSponsorColumbia UniversityRan2020 to 2022Enrolled60,893ConditionsHospital Acquired ConditionArmsCONCERN CDS system notification
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Characterizing Basic and Complex Usage of i2b2 at an Academic Medical Center.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2020
    Article
  3. Web services for data warehouses: OMOP and PCORnet on i2b2.Journal of the American Medical Informatics Association : JAMIA · 2018
    Article
  4. Article
  5. Review
  6. Automated Population of an i2b2 Clinical Data Warehouse using FHIR.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2018
    Article
  7. Article
  8. Article
  9. Article
  10. SMART-on-FHIR implemented over i2b2.Journal of the American Medical Informatics Association : JAMIA · 2017
    Article
  11. Evolving Research Data Sharing Networks to Clinical App Sharing Networks.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
  12. Review
  13. Supporting Multi-sourced Medication Information in i2b2.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jeffrey G KlannPartners Healthcare, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA.
Michael MendisPartners Healthcare, Boston, Massachusetts, USA.
Lori C PhillipsPartners Healthcare, Boston, Massachusetts, USA.
Alyssa P GoodsonPartners Healthcare, Boston, Massachusetts, USA.
Beatriz H RochaPartners Healthcare, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA Brigham and Women's Hospital, Boston, Massachusetts, USA.
Howard S GoldbergPartners Healthcare, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA Brigham and Women's Hospital, Boston, Massachusetts, USA.
Nich WattanasinPartners Healthcare, Boston, Massachusetts, USA.
Shawn N MurphyPartners Healthcare, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA.

Funding

Instrumenting i2b2 for Improved Medication Research: Adding the Patient VoiceR01GM104303 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2013 to 2016
$1.6M
NIGMS NIH HHS 5R01GM104303-02NLM NIH HHS U54LM00874
6 · The paper itself

Abstract

objectiveClinical data warehouses have accelerated clinical research, but even with available open source tools, there is a high barrier to entry due to the complexity of normalizing and importing data. The Office of the National Coordinator for Health Information Technology's Meaningful Use Incentive Program now requires that electronic health record systems produce standardized consolidated clinical document architecture (C-CDA) documents. Here, we leverage this data source to create a low volume standards based import pipeline for the Informatics for Integrating Biology and the Bedside (i2b2) clinical research platform. We validate this approach by creating a small repository at Partners Healthcare automatically from C-CDA documents. MATERIALS AND

methodsWe designed an i2b2 extension to import C-CDAs into i2b2. It is extensible to other sites with variances in C-CDA format without requiring custom code. We also designed new ontology structures for querying the imported data.

resultsWe implemented our methodology at Partners Healthcare, where we developed an adapter to retrieve C-CDAs from Enterprise Services. Our current implementation supports demographics, encounters, problems, and medications. We imported approximately 17 000 clinical observations on 145 patients into i2b2 in about 24 min. We were able to perform i2b2 cohort finding queries and view patient information through SMART apps on the imported data. DISCUSSION: This low volume import approach can serve small practices with local access to C-CDAs and will allow patient registries to import patient supplied C-CDAs. These components will soon be available open source on the i2b2 wiki.

conclusionsOur approach will lower barriers to entry in implementing i2b2 where informatics expertise or data access are limited.

Indexed as

Biomedical ResearchContinuity of Patient CareDatabases as TopicInformation Storage and RetrievalDatabase Management SystemsHumansMeaningful UseSystems IntegrationDatabase Management SystemsInformation Storage and RetrievalMeaningful UseMedical InformaticsSystems Integration

Identifiers

PMID25352566
PMCPMC6080729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.