Evidence map›Paper›PMID 25352451›Full record

ArticleJournal of Alzheimer's disease : JAD2015

Arterial wall function is associated with cognitive performance primarily in elderly with type 2 diabetes.

Ramit Ravona-Springer, Salo Haratz, David Tanne, James Schmeidler, Shai Efrati, Clive Rosendorff, Michal Schnaider Beeri, Jeremy M Silverman

Open access · greenAbstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ramit Ravona-SpringerMemory Clinic, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Salo HaratzSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel Stroke Unit, Neurology Department, Sheba Medical Center, Ramat Gan, Israel.
David TanneSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel Stroke Unit, Neurology Department, Sheba Medical Center, Ramat Gan, Israel.
James SchmeidlerDepartment of Psychiatry at the Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shai EfratiSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel The institute of Hyperbaric Medicine, Assaf Harofeh Medical Center, Zerifin, Israel Research and Development Unit, Assaf Harofeh Medical Center, Zerifin, Israel Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv, Israel.
Clive RosendorffJames J. Peters Veterans Affairs Medical Center, Bronx, NY, USA Department of Medicine, (Cardiology), Mount Sinai School of Medicine, New York, NY, USA.
Michal Schnaider BeeriDepartment of Psychiatry at the Icahn School of Medicine at Mount Sinai, New York, NY, USA Josef Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.
Jeremy M SilvermanDepartment of Psychiatry at the Icahn School of Medicine at Mount Sinai, New York, NY, USA James J. Peters Veterans Affairs Medical Center, Bronx, NY, USA.
Sheba Medical Center · ILIcahn School of Medicine at Mount Sinai · USJames J. Peters VA Medical Center · USTel Aviv University · IL

Funding

QUANTITATIVE ANALYSIS OF MICROVASCULAR CHANGES IN THE AGING BRAINP01AG002219 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI HAROUTUNIAN, VAHRAM · 1985 to 2009
$19.2M
Inflammation, long-term diabetes characteristics, and cognitive declineR01AG034087 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCHNAIDER BEERI, MICHAL · 2009 to 2014
$3.7M
NIA NIH HHS AG02219NIA NIH HHS P01 AG002219NIA NIH HHS P01-AG02219NIA NIH HHS R01 AG034087
6 · The paper itself

Abstract

Regression analyses compared 41 type 2 diabetes (T2D) and 131 non-T2D cognitively normal elderly males on the associations of arterial wall function measures [large artery elasticity index (LAEI), small artery elasticity index (SAEI), systemic vascular resistance (SVR), and total vascular impedance (TVI)] with cognitive performance (memory, language, and executive functions), controlling for socio-demographic and cardiovascular factors. Higher LAEI and lower TVI were significantly associated with better executive functions performance in T2D but not in non-T2D subjects. Lower TVI was more associated with better language performance in T2D. Results suggest that arterial wall function is associated with cognition in T2D.

Indexed as

Aged, 80 and overBlood PressureCognitionDiabetes Mellitus, Type 2Executive FunctionHumansLanguageMaleMemoryNeuropsychological TestsRegression AnalysisVascular ResistanceVeteransArterial wall functioncognitive functionlarge artery elasticity indextotal vascular impedancetype 2 diabetes

Identifiers

PMID25352451
PMCPMC5754925
OpenAlexW1122627960

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.