ArticleJournal of endocrinological investigation2015
Evaluation of epicardial fat tissue thickness as a marker of cardiovascular risk in patients with subclinical hypothyroidism.
Article in Journal of endocrinological investigation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- The Importance of the Assessment of Epicardial Adipose Tissue in Scientific Research.Journal of clinical medicine · 2022Review
- Subclinical Hypothyroidism Represents Visceral Adipose Indices, Especially in Women With Cardiovascular Risk.Journal of the Endocrine Society · 2021Article
- Early L-T4 intervention improves fetal heart development in pregnant rats with subclinical hypothyroidism rats by activating BMP4/Smad4 signaling pathway.BMC cardiovascular disorders · 2020Article
- Thyroid function and atrial fibrillation: Is there a mediating role for epicardial adipose tissue?Clinical epidemiology · 2018Article
- Reply to the Letter to the Editor for the Article Entitled "Epicardial Adiposity is Associated with Microalbuminuria in Patients with Essential Hypertension" Published in the Journal of Acta Cardiologica Sinica in 2017 (2017;33:74-80).Acta Cardiologica Sinica · 2017Article
- Epicardial fat thickness and oxidative stress parameters in patients with subclinical hypothyroidism.Archives of medical science : AMS · 2017Article
- Usefulness of the epicardial fat tissue thickness as a diagnostic criterion for geriatric patients with metabolic syndrome.Journal of geriatric cardiology : JGC · 2015Article
- The Association between Subclinical Hypothyroidism and Epicardial Adipose Tissue Thickness.Korean circulation journal · 2015Article
- Cardiovascular Risk Assessment in Subclinical Hypothyroid Individuals with Thyroid-stimulating Hormone <10 uIU/ml.Indian journal of endocrinology and metabolismArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEpicardial fat thickness (EFT) has been evaluated as a marker of cardiovascular disease, with good correlation with classical cardiovascular risk factors in the general population. The aim of this study was to evaluate the EFT in subclinical hypothyroidism (SCH), in comparison to a group without thyroid dysfunction.
methodsA cross-sectional study was performed with 100 participants, including 52 SCH patients and 48 individuals without any thyroid dysfunction (euthyroid group-EU). Transthoracic echocardiography (TE), thyroid hormone levels, lipid profile, and assessment of body composition by bioelectrical impedance (BIA) and anthropometry were measured in all subjects.
resultsThe SCH and EU groups were comparable with respect to age, gender, and Framingham risk scores. Serum thyroid-stimulating hormone (TSH) was 6.7 ± 1.4 mIU/L in the SCH group and 2.0 ± 0.84 mIU/L in the control group. EFT was similar in both groups (SCH 3.5 ± 1.3 mm, EU 3.5 ± 1.1 mm, p = 0.43). EFT showed a slight trend for a positive correlation with serum TSH in the SCH group (r s = 0.263, p = 0.05). EFT correlated with the body fat percentage in the SCH group (r s = 0.350, p = 0.03) and EU group (r s = 0.033, p = 0.04). EFT in this cohort was not independently correlated to changes in TSH and Framingham risk score.
conclusionsEFT determination by TE does not seem to be a good marker of cardiovascular risk in SCH patients with serum TSH <10.0 mIU/L and no pre-existing cardiovascular morbidity.
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