Evidence map›Paper›PMID 25352233›Full record

ArticleJournal of clinical and experimental neuropsychology2014

Better adherence to treatment recommendations in heart failure predicts improved cognitive function at a one-year follow-up.

Michael L Alosco, Mary Beth Spitznagel, Ronald Cohen, Lawrence H Sweet, Richard Josephson, Joel Hughes, Jim Rosneck, John Gunstad

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Observational
  6. International journal of MS care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael L Aloscoa Department of Psychological Sciences , Kent State University , Kent , OH , USA.
Mary Beth Spitznagel
Ronald Cohen
Lawrence H Sweet
Richard Josephson
Joel Hughes
Jim Rosneck
John Gunstad

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Cognitive Benefits of Cardiac Rehabilitation in Heart FailureR01HL089311 · NHLBI · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2008 to 2012
$2.6M
Hemodynamic and Cognitive Function in Cardiovascular DiseaseR01HL084178 · NHLBI · BUTLER HOSPITAL (PROVIDENCE, RI) · PI SWEET, LAWRENCE H · 2007 to 2011
$2.4M
HEART DISEASE, CNS DYSFUNCTION &OUTCOME IN THE ELDERLYR01AG017975 · NIA · MIRIAM HOSPITAL · PI COHEN, RONALD A · 2000 to 2004
$1.5M
Cognitive Effects of Bariatric SurgeryR01DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2006 to 2009
$1.5M
Extended Effects of Bariatric Surgery on Cognitive FunctionR56DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2010 to 2010
$296k
NHLBI NIH HHS HL089311NHLBI NIH HHS R01 HL084178NHLBI NIH HHS R01 HL089311NIA NIH HHS P30 AG028740NIA NIH HHS R01 AG017975NIDDK NIH HHS DK075119NIDDK NIH HHS R01 DK075119NIDDK NIH HHS R56 DK075119
6 · The paper itself

Abstract

introductionTreatment nonadherence is common in heart failure (HF) and is associated with poor health outcomes in this population. Recent cross-sectional work in heart failure and past work in other medical populations suggest that cognitive function is a key determinant of a patient's ability to adhere to treatment recommendations. However, it is also possible that treatment adherence is an important modifier and predictor of cognitive function, though no study has examined this possibility, and we sought to do so in a sample of heart failure patients.

methodA total of 115 patients with heart failure self-reported adherence to treatment recommendations. The Modified Mini Mental State Examination (3MS), Trail Making Test Parts A and B, and the California Verbal Learning Test-II (CVLT-II) assessed cognitive function. These procedures were performed at baseline and a 12-month follow-up.

resultsGlobal cognition and memory abilities improved over the 12-month period. Regression analyses controlling for baseline and medical and demographic factors showed that better baseline treatment adherence predicted improved 12-month performances on the 3MS and CVLT-II. Adherence to medication and diet regimens and smoking abstinence emerged as the most important contributors.

conclusionsBetter treatment adherence predicted improved cognition one year later in HF. Prospective studies that utilize objective assessments of treatment adherence are needed to confirm our findings and examine whether improved treatment adherence preserves cognitive function in heart failure.

Indexed as

AgedAged, 80 and overAnalysis of VarianceCognition DisordersCross-Sectional StudiesDepressionFemaleFollow-Up StudiesHeart FailureHumansMaleMental Status ScheduleMiddle AgedNeuropsychological TestsPatient CompliancePredictive Value of TestsCognitive functionHeart failureLongitudinalTreatment adherence

Identifiers

PMID25352233
PMCPMC4994527

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.