Evidence map›Paper›PMID 25351547›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo

HIV and HCV coinfection: prevalence, associated factors and genotype characterization in the Midwest Region of Brazil.

Solange Zacalusni Freitas, Sheila Araújo Teles, Paulo Cesar Lorenzo, Marco Antonio Moreira Puga, Tayana Serpa Ortiz Tanaka, Danilo Yamamoto Thomaz, Regina Maria Bringel Martins, Angelita Fernandes Druzian, Andréa Siqueira Campos Lindenberg, Marina Sawada Torres and 4 more

Abstract read
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. [Epidemiology of hepatitis C virus infection in ColombiaEpidemiologia da infecção pelo vírus da hepatite C na Colômbia].Revista panamericana de salud publica = Pan American journal of public health · 2021
    Article
  7. Article
  8. Prevalence and characteristics of HIV/HBV and HIV/HCV coinfections in Tuscany.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Solange Zacalusni FreitasFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Sheila Araújo TelesFederal University of Goiás, Goiânia, GO, Brazil.
Paulo Cesar LorenzoFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Marco Antonio Moreira PugaFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Tayana Serpa Ortiz TanakaFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Danilo Yamamoto ThomazFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Regina Maria Bringel MartinsFederal University of Goiás, Goiânia, GO, Brazil.
Angelita Fernandes DruzianFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Andréa Siqueira Campos LindenbergFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Marina Sawada TorresHematology and Hemotherapy Center of Mato Grosso do Sul, Campo Grande, MS, Brazil.
Sérgio A PereiraLaboratory of Viral Hepatitis, Rio de Janeiro, RJ, Brazil.
Livia Melo VillarLaboratory of Viral Hepatitis, Rio de Janeiro, RJ, Brazil.
Elisabete LampeLaboratory of Viral Hepatitis, Rio de Janeiro, RJ, Brazil.
Ana Rita Coimbra Motta-CastroFederal University of Mato Grosso do Sul, Campo Grande, MS, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cross-sectional study on prevalence, associated factors and genotype distribution of HCV infection was conducted among 848 HIV-infected patients recruited at reference centers in the Midwest Region of Brazil. The prevalence rate of HIV-HCV coinfection was 6.9% (95% CI: 5.2 to 8.6). In multivariable analysis, increasing age, use of illicit drugs (injection and non-injection), a history of blood transfusion before 1994, and the absence of a steady partnership were significant independent associated factors for HIV-HCV coinfection. The phylogenetic analysis based on the NS5B region revealed the presence of two major circulating genotypes of HCV: genotypes 1 (58.3%) and 3 (41.7%). The prevalence of HIV-HCV coinfection was lower than those reported in studies conducted with HIV-infected patients in different regions of Brazil, due to the fact that illicit drug use is not a frequent mode of HIV transmission in this region of Brazil. Serologic screening of HIV-patients for HCV before initiating antiretroviral treatment, a comprehensive identification of associated factors, and the implementation of effective harm reduction programs are highly recommended to provide useful information for treatment and to prevent HCV coinfection in these patients.

Indexed as

AdultBrazilCoinfectionCross-Sectional StudiesFemaleGenotypeHepacivirusHepatitis CHIV InfectionsHumansMaleMiddle AgedPhylogenyPrevalenceRisk FactorsRNA, ViralRNA, Viral

Identifiers

PMID25351547
PMCPMC4296873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.