Evidence map›Paper›PMID 25350972›Full record

ReviewParasite (Paris, France)2014

Selection methods for resistance to and tolerance of helminths in livestock.

Concepta McManus, Tiago do Prado Paim, Cristiano Barros de Melo, Bruno S A F Brasil, Samuel R Paiva

Open access · goldAbstract readReview
In one paragraph

Review in Parasite (Paris, France), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Concepta McManusVice-Coordinator INCT-Pecuaria, Universidade Federal do Rio Grande do Sul, Departamento de Zootecnia, Av. Bento Gonçalves, CEP 91540-000 Porto Alegre, Rio Grande do Sul, Brazil - Universidade de Brasília, Campus Darcy Ribeiro, 70910-900 Asa Norte, Brasilia, Distrito Federal, Brazil.
Tiago do Prado PaimINCT - Pecuaria, Universidade Federal de Minas Gerais, 30161-970 Belo Horizonte, Brazil - Instituto Federal de Educação, Ciência e Tecnologia Goiano - Campus Iporá, Avenida Oeste s/n, saída para Piranhas, CEP 76.200-000 Iporá, Goiás, Brazil.
Cristiano Barros de MeloUniversidade de Brasília, Campus Darcy Ribeiro, 70910-900 Asa Norte, Brasilia, Distrito Federal, Brazil - INCT - Pecuaria, Universidade Federal de Minas Gerais, 30161-970 Belo Horizonte, Brazil.
Bruno S A F BrasilEMBRAPA Agroenergia, Final W3 Norte, 70770-901 Brasília, Brazil.
Samuel R PaivaSecretaria de Relações Internacionais, Embrapa, Final W5 Norte, 70770-901 Brasília, Brazil - EMBRAPA Recursos Genéticos e Biotecnologia, Final W5 Norte, 70770-901 Brasília, Brazil.
Brazilian Agricultural Research Corporation · BRInstituto Federal Goiano · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helminthiases are among the most important livestock diseases worldwide, in particular for small ruminants, which are the focus of this review. Resource Allocation Theory implies that high-productivity farm animals proportionate insufficient resources for adequate coping with stressful conditions. Significant differences between breeds and within breeds are seen, as well as genotype vs. environment interactions. With improvement of genetic host resistance to infection, transmission of infection will be impacted. On the other hand, genetic improvement of resilience can lead to a reduction in clinical signs of disease, but not necessarily reduce transmission of infection to other animals. Faecal egg count (FEC) is the main measurement used to evaluate helminthiasis load, despite the fact that the protocols and analytical methods can affect the results, and the FEC data frequently shows aggregative, negative skewed distribution, and a high coefficient of variation. Mass selection where heritability is generally medium to low generally produces slow results and low economic returns. Many studies have been published linking resistance to nematodes in livestock to Quantitative Trait Loci and most studies have concentrated on chromosomes where the major histocompatibility complex region is located. Nevertheless, these complex traits have been seen to be affected by thousands of variants that each has a small effect. More recent studies have shown that genome-wide selection strategies can be useful in selecting animals for improved production and resistance traits in this case.

Indexed as

Selection, GeneticAllelesAnimal HusbandryAnimalsAnthelminticsBiomarkersBreedingDisease ResistanceDrug ResistanceEvolution, MolecularGene-Environment InteractionGenetic Association StudiesGenetics, PopulationGenome-Wide Association StudyGoat DiseasesGoatsAnthelminticsBiomarkers

Identifiers

PMID25350972
PMCPMC4211276
OpenAlexW2129451024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.