Evidence map›Paper›PMID 25350546›Full record

Trial reportPloS one2014

The impact of text message reminders on adherence to antimalarial treatment in northern Ghana: a randomized trial.

Julia R G Raifman, Heather E Lanthorn, Slawa Rokicki, Günther Fink

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01722734 nacompletednot on this map

Preserving ACTs - Text Reminders to Increase Adherence to ACT Treatment

TypeinterventionalSponsorHarvard School of Public Health (HSPH)Ran2011 to 2013Enrolled1,140ConditionsMalariaArmsText message reminders
NCT03117842 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Using a Theory-based SMS/VM Intervention to Improve Sexual and Reproductive Health of Female Entertainment Workers in Cambodia: Study Protocol of a Randomized Controlled Trial

TypeinterventionalSponsorTouro University, CaliforniaRan2018 to 2019Enrolled600ConditionsReproductive Health, Sexual HealthArmsAutomated text and voice messages
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Julia R G RaifmanDepartment of Global Health and Population, Harvard School of Public Health, Boston, MA, United States of America.
Heather E LanthornHarvard School of Public Health, Boston, MA, United States of America.
Slawa RokickiDepartment of Health Policy, Harvard Graduate School of Arts and Sciences, Cambridge, MA, United States of America.
Günther FinkDepartment of Global Health and Population, Harvard School of Public Health, Boston, MA, United States of America.
Harvard Global Health Institute · USHarvard University · US

Funding

HEALTH POLICY TRAINING PROGRAMT32HS000055 · AHRQ · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI CUTLER, DAVID M · 1994 to 2024
$7.1M
AHRQ HHS T32 HS000055
6 · The paper itself

Abstract

backgroundLow rates of adherence to artemisinin-based combination therapy (ACT) regimens increase the risk of treatment failure and may lead to drug resistance, threatening the sustainability of current anti-malarial efforts. We assessed the impact of text message reminders on adherence to ACT regimens.

methodsHealth workers at hospitals, clinics, pharmacies, and other stationary ACT distributors in Tamale, Ghana provided flyers advertising free mobile health information to individuals receiving malaria treatment. The messaging system automatically randomized self-enrolled individuals to the control group or the treatment group with equal probability; those in the treatment group were further randomly assigned to receive a simple text message reminder or the simple reminder plus an additional statement about adherence in 12-hour intervals. The main outcome was self-reported adherence based on follow-up interviews occurring three days after treatment initiation. We estimated the impact of the messages on treatment completion using logistic regression.

results1140 individuals enrolled in both the study and the text reminder system. Among individuals in the control group, 61.5% took the full course of treatment. The simple text message reminders increased the odds of adherence (adjusted OR 1.45, 95% CI [1.03 to 2.04], p-value 0.028). Receiving an additional message did not result in a significant change in adherence (adjusted OR 0.77, 95% CI [0.50 to 1.20], p-value 0.252).

conclusionThe results of this study suggest that a simple text message reminder can increase adherence to antimalarial treatment and that additional information included in messages does not have a significant impact on completion of ACT treatment. Further research is needed to develop the most effective text message content and frequency.

trial registrationClinicalTrials.gov NCT01722734.

Indexed as

Medication AdherenceReminder SystemsText MessagingAdolescentAdultAgedAntimalarialsChildChild, PreschoolFemaleGhanaHumansInfantMalariaMaleMiddle AgedAntimalarials

Identifiers

PMID25350546
PMCPMC4211682
OpenAlexW2022498633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.