ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2014
Primitive endoderm differentiation: from specification to epithelium formation.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Distinct roles for SETα and SETβ in early cell fate decisions.Nucleic acids research · 2026Article
- Coping with uncertainty: Challenges for robust pattern formation in dynamical tissues.Seminars in cell & developmental biology · 2025Review
- Article
- An integrated approach identifies the molecular underpinnings of murine anterior visceral endoderm migration.Developmental cell · 2024Article
- Cell fate decision by a morphogen-transcription factor-chromatin modifier axis.Nature communications · 2024Article
- Tissue-intrinsic beta-catenin signals antagonize Nodal-driven anterior visceral endoderm differentiation.Nature communications · 2024Article
- The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency.Nature communications · 2023Article
- A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression.Development (Cambridge, England) · 2022Article
- Characterization of multitype colonies originating from porcine blastocysts producedFrontiers in cell and developmental biology · 2022Article
- Cell fate determination and Hippo signaling pathway in preimplantation mouse embryo.Cell and tissue research · 2021Review
- Cooperation between HDAC3 and DAX1 mediates lineage restriction of embryonic stem cells.The EMBO journal · 2021Article
- Dynamic conversion of cell sorting patterns in aggregates of embryonic stem cells with differential adhesive affinity.BMC developmental biology · 2021Article
- Unraveling the Spatiotemporal Human Pluripotency in Embryonic Development.Frontiers in cell and developmental biology · 2021Review
- A DNA methylation state transition model reveals the programmed epigenetic heterogeneity in human pre-implantation embryos.Genome biology · 2020Article
- Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid.Developmental cell · 2019Article
- Roles of MicroRNAs in Establishing and Modulating Stem Cell Potential.International journal of molecular sciences · 2019Review
- Transition of inner cell mass to embryonic stem cells: mechanisms, facts, and hypotheses.Cellular and molecular life sciences : CMLS · 2019Review
- Mesenchymal-epithelial transition in development and reprogramming.Nature cell biology · 2019Review
- GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm.Developmental biology · 2018Article
- A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.Nature communications · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In amniotes, primitive endoderm (PrE) plays important roles not only for nutrient support but also as an inductive tissue required for embryo patterning. PrE is an epithelial monolayer that is visible shortly before embryo implantation and is one of the first three cell lineages produced by the embryo. We review here the molecular mechanisms that have been uncovered during the past 10 years on PrE and epiblast cell lineage specification within the inner cell mass of the blastocyst and on their subsequent steps of differentiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.