Evidence map›Paper›PMID 25349195›Full record

ReviewEndocrine-related cancer2015

Models of neuroendocrine prostate cancer.

Lisa D Berman-Booty, Karen E Knudsen

Open access · bronzeAbstract readReview
In one paragraph

Review in Endocrine-related cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lisa D Berman-BootyDepartment of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA Department of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA.
Karen E KnudsenDepartment of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA Department of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA Department of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA Department of Cancer BiologyKimmel Cancer CenterDepartments of UrologyRadiation OncologyThomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA Karen.Knudsen@Jefferson.edu.
Thomas Jefferson University · US

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Andrew Chapman · 1995 to 2026
$94.8M
SWI/SNF dysregulation in development and diseaseR01CA159945 · NCI · THOMAS JEFFERSON UNIVERSITY · PI KNUDSEN, KAREN E · 2012 to 2016
$1.6M
Inhibition of Prostate Carcinogenesis & Tumor Growth by Energy Restriction-MimetiK01OD010463 · OD · THOMAS JEFFERSON UNIVERSITY · PI BERMAN-BOOTY, LISA DANIELLE · 2012 to 2014
$390k
NCI NIH HHS P30 CA056036NCI NIH HHS R01 CA 159945NCI NIH HHS R01 CA159945NIH HHS K01 OD010463
6 · The paper itself

Abstract

Prostate cancer remains the second leading cause of cancer death in men in the USA and most western countries. Prostatic acinar adenocarcinoma is the most commonly diagnosed form of prostate cancer. Small-cell neuroendocrine carcinoma is less frequently identified at the time of initial diagnosis, but this highly aggressive form of prostate cancer is increasingly observed in patients who have failed first- and second-line hormone therapy. Thus, developing and exploring models of neuroendocrine prostate cancer (NePC) are of increasing importance. This review examines the relevant xenograft tumor and genetically engineered mouse models of NePC, with the aim of addressing salient features and clinical relevance.

Indexed as

Disease Models, AnimalAnimalsCarcinoma, NeuroendocrineHeterograftsHumansMaleMiceProstatic Neoplasmscastration-resistant prostate cancergenetically engineered miceneuroendocrine prostate cancerxenograft tumors

Identifiers

PMID25349195
PMCPMC6481630
OpenAlexW2074737073

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.