Evidence map›Paper›PMID 25348854›Full record

ReviewCancer prevention research (Philadelphia, Pa.)2015

Toxic phytochemicals and their potential risks for human cancer.

Ann M Bode, Zigang Dong

Abstract readReview
In one paragraph

Review in Cancer prevention research (Philadelphia, Pa.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Neoplasia in the dromedary camel: a review (Frontiers in veterinary science · 2025
    Review
  5. Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.Bioengineering (Basel, Switzerland) · 2024
    Review
  6. Review
  7. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  8. Safety evaluation ofRSC advances · 2024
    Article
  9. Aqueous Extracts ofInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Effect of Karas (Tropical life sciences research · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ann M BodeThe Hormel Institute, University of Minnesota, Austin, Minnesota.
Zigang DongThe Hormel Institute, University of Minnesota, Austin, Minnesota. zgdong@hi.umn.edu.

Funding

Ultraviolet-Induced Signal TrasductionR01CA077646 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DONG, ZIGANG · 1999 to 2010
$2.3M
The role of histone phosphorylation in arsenic-induced cell transformation and skR01ES016548 · NIEHS · UNIVERSITY OF MINNESOTA · PI DONG, ZIGANG · 2008 to 2012
$1.7M
Anticarcinogenic Mechanisms of Tea ConstituentsR37CA081064 · NCI · UNIVERSITY OF MINNESOTA · PI DONG, ZIGANG · 2008 to 2012
$1.5M
Mechanisms of chemopreventive effect of resveratrolR01CA111536 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI DONG, ZIGANG · 2005 to 2009
$1.4M
Inhibition of Carcinogenesis by Tea and Tea ConstituentsR01CA120388 · NCI · UNIVERSITY OF MINNESOTA · PI DONG, ZIGANG · 2006 to 2010
$1.3M
NCI NIH HHS CA077646NCI NIH HHS CA111536NCI NIH HHS CA120388NCI NIH HHS R01 CA077646NCI NIH HHS R01 CA111536NCI NIH HHS R01 CA120388NCI NIH HHS R37 CA081064NCI NIH HHS R37CA081064NIEHS NIH HHS ES016548NIEHS NIH HHS R01 ES016548
6 · The paper itself

Abstract

Consuming plants for their presumed health benefits has occurred since early civilizations. Phytochemicals are found in various plants that are frequently included in the human diet and are generally thought to be safe for consumption because they are produced naturally. However, this is not always the case and in fact many natural compounds found in several commonly consumed plants are potential carcinogens or tumor promoters and should be avoided.

Indexed as

PhytotherapyAmygdalinAristolochic AcidsCapsaicinCell Line, TumorCycasinDietDrug Screening Assays, AntitumorHumansIndansNeoplasmsPhorbol EstersPhytochemicalsPhytoestrogensPlant ExtractsPlantsAmygdalinAristolochic AcidsCapsaicinCycasinIndansPhorbol EstersPhytochemicalsPhytoestrogensPlant ExtractsptaquilosidePyrrolizidine AlkaloidsSafroleSesquiterpenes

Identifiers

PMID25348854
PMCPMC4289646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.