Evidence map›Paper›PMID 25348401›Full record

ArticleNucleic acids research2015

The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease.

Janan T Eppig, Judith A Blake, Carol J Bult, James A Kadin, Joel E Richardson, Mouse Genome Database Group

Abstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 241 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
241citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

241 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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181 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janan T EppigThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA janan.eppig@jax.org.
Judith A BlakeThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Carol J BultThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
James A KadinThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Joel E RichardsonThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Mouse Genome Database Group

Funding

SOFTWARE AND DATABASE SYSTEM DEVELOPMENTP41HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1995 to 2010
$72.1M
Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI Mark D ADAMS · 1985 to 2026
$61.9M
Mouse Genome DatabaseU41HG000330 · NHGRI · JACKSON LABORATORY · PI BLAKE, JUDITH A, BULT, CAROL J · 2011 to 2020
$45.5M
MULTI-LEVEL ANALYSIS AND DISPLAY OF MOUSE GENOME DATAP01HG000330 · NHGRI · JACKSON LABORATORY · PI EPPIG, JANAN T. · 1990 to 1994
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NCI NIH HHS P30 CA034196NHGRI NIH HHS HG000330NHGRI NIH HHS U41 HG000330
6 · The paper itself

Abstract

The Mouse Genome Database (MGD, http://www.informatics.jax.org) serves the international biomedical research community as the central resource for integrated genomic, genetic and biological data on the laboratory mouse. To facilitate use of mouse as a model in translational studies, MGD maintains a core of high-quality curated data and integrates experimentally and computationally generated data sets. MGD maintains a unified catalog of genes and genome features, including functional RNAs, QTL and phenotypic loci. MGD curates and provides functional and phenotype annotations for mouse genes using the Gene Ontology and Mammalian Phenotype Ontology. MGD integrates phenotype data and associates mouse genotypes to human diseases, providing critical mouse-human relationships and access to repositories holding mouse models. MGD is the authoritative source of nomenclature for genes, genome features, alleles and strains following guidelines of the International Committee on Standardized Genetic Nomenclature for Mice. A new addition to MGD, the Human-Mouse: Disease Connection, allows users to explore gene-phenotype-disease relationships between human and mouse. MGD has also updated search paradigms for phenotypic allele attributes, incorporated incidental mutation data, added a module for display and exploration of genes and microRNA interactions and adopted the JBrowse genome browser. MGD resources are freely available to the scientific community.

Indexed as

Databases, GeneticGenomeAllelesAnimalsDiseaseGenesGenomicsHumansInternetMiceModels, AnimalMutationPhenotype

Identifiers

PMID25348401
PMCPMC4384027

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.