ArticleMolecular plant pathology2015
Folic acid induces salicylic acid-dependent immunity in Arabidopsis and enhances susceptibility to Alternaria brassicicola.
Article in Molecular plant pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Folate transporters at the plasma membrane of fungi and plants: specificity, mechanism of transport, and importance.Biochemical Society transactions · 2026Review
- Article
- Multi-omic analysis of the extension of broccoli quality during storage by folic acid.Journal of advanced research · 2024Article
- Comparative genomic analysis ofMicrobial genomics · 2023Article
- Role of miRNAs in regulation of SA-mediated upregulation of genes involved in folate and methionine metabolism in foxtail millet.Frontiers in plant science · 2022Article
- Biosolid-Amended Soil Enhances Defense Responses in Tomato Based on Metagenomic Profile and Expression of Pathogenesis-Related Genes.Plants (Basel, Switzerland) · 2021Article
- The 5-formyl-tetrahydrofolate proteome links folates with C/N metabolism and reveals feedback regulation of folate biosynthesis.The Plant cell · 2021Article
- Mycotoxin Uptake in Wheat - EavesdroppingFrontiers in plant science · 2021Article
- Identification and analysis of key genes involved in methyl salicylate biosynthesis in different birch species.PloS one · 2020Article
- Salicylic acid in Populus tomentosa is a remote signalling molecule induced by Botryosphaeria dothidea infection.Scientific reports · 2018Article
- The manipulation of gene expression and the biosynthesis of Vitamin C, E and folate in light-and dark-germination of sweet corn seeds.Scientific reports · 2017Article
- Monoterpenes Support Systemic Acquired Resistance within and between Plants.The Plant cell · 2017Article
- The defence-associated transcriptome of hexaploid wheat displays homoeolog expression and induction bias.Plant biotechnology journal · 2017Article
- Distinctive features and differential regulation of the DRTS genes of Arabidopsis thaliana.PloS one · 2017Article
- Folates in Plants: Research Advances and Progress in Crop Biofortification.Frontiers in chemistry · 2017Review
- Vitamins for enhancing plant resistance.Planta · 2016Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Folates are essential for one-carbon transfer reactions in all organisms and contribute, for example, to de novo DNA synthesis. Here, we detected the folate precursors 7,8-dihydropteroate (DHP) and 4-amino-4-deoxychorismate (ADC) in extracts from Arabidopsis thaliana plants by Fourier transform ion cyclotron resonance-mass spectrometry. The accumulation of DHP, but not ADC, was induced after infection of plants with Pseudomonas syringae delivering the effector protein AvrRpm1. Application of folic acid or the DHP precursor 7,8-dihydroneopterin (DHN) enhanced resistance in Arabidopsis to P. syringae and elevated the transcript accumulation of the salicylic acid (SA) marker gene pathogenesis-related1 in both the treated and systemic untreated leaves. DHN- and folic acid-induced systemic resistance was dependent on SA biosynthesis and signalling. Similar to SA, folic acid application locally enhanced Arabidopsis susceptibility to the necrotrophic fungus Alternaria brassicicola. Together, the data associate the folic acid pathway with innate immunity in Arabidopsis, simultaneously activating local and systemic SA-dependent resistance to P. syringae and suppressing local resistance to A. brassicicola.
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