Evidence map›Paper›PMID 25347403›Full record

ArticleNano letters2014

DNA translocations through solid-state plasmonic nanopores.

Francesca Nicoli, Daniel Verschueren, Misha Klein, Cees Dekker, Magnus P Jonsson

Abstract read
In one paragraph

Article in Nano letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Localized Nanopore Fabrication via Controlled Breakdown.Nanomaterials (Basel, Switzerland) · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Sensitivity-Enhancing Strategies in Optical Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  14. Article
  15. Functionalized Nanogap for DNA Read-Out: Nucleotide Rotation and Current-Voltage Curves.Chemphyschem : a European journal of chemical physics and physical chemistry · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Francesca NicoliDepartment of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology , Lorentzweg 1, 2628 CJ Delft, The Netherlands.
Daniel Verschueren
Misha Klein
Cees Dekker
Magnus P Jonsson

Funding

Plasmonic nanopores for trapping, controlled motion and sequencing of DNAR01HG007406 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI AKSIMENTIEV, ALEKSEI · 2013 to 2016
$2.4M
European Research Council 247072NHGRI NIH HHS 1R01HG007406-01NHGRI NIH HHS R01 HG007406
6 · The paper itself

Abstract

Nanopores enable label-free detection and analysis of single biomolecules. Here, we investigate DNA translocations through a novel type of plasmonic nanopore based on a gold bowtie nanoantenna with a solid-state nanopore at the plasmonic hot spot. Plasmonic excitation of the nanopore is found to influence both the sensor signal (nanopore ionic conductance blockade during DNA translocation) and the process that captures DNA into the nanopore, without affecting the duration time of the translocations. Most striking is a strong plasmon-induced enhancement of the rate of DNA translocation events in lithium chloride (LiCl, already 10-fold enhancement at a few mW of laser power). This provides a means to utilize the excellent spatiotemporal resolution of DNA interrogations with nanopores in LiCl buffers, which is known to suffer from low event rates. We propose a mechanism based on plasmon-induced local heating and thermophoresis as explanation of our observations.

Indexed as

Biosensing TechniquesDNAGoldLightMetal NanoparticlesMotionNanoporesSurface Plasmon ResonanceDNAGoldbiosensingDNANanoporesplasmonicssingle-molecule sensingthermophoresis

Identifiers

PMID25347403
PMCPMC4264857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.