ReviewThe Canadian journal of urology2014
Temporal trends and racial disparities in global prostate cancer prevalence.
Review in The Canadian journal of urology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Prostate cancer metastasis and health disparities: a systematic review.Prostate cancer and prostatic diseases · 2024Pooled it
- Prevalence of incidental prostate cancer: A systematic review of autopsy studies.International journal of cancer · 2015Pooled it
- A randomized controlled trial evaluating the effect of low-dose chlormadinone in patients with low-risk prostate cancer: PROSAS study.Japanese journal of clinical oncology · 2022Trial
- Comparative Analysis of Alcohol and Aldehyde Dehydrogenase Activities in Prostate Cancer and Benign Prostatic Hyperplasia.Journal of clinical medicine · 2026Article
- Early-Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection.MedComm · 2026Review
- Obesity-linked genes may promote prostate cancer among Asian and Hispanic immigrants to North America.Frontiers in public health · 2026Review
- Prostate Cancer Among Patients Presenting with Obstructive Lower Urinary Tract Symptoms at a Tertiary Hospital in South Western Uganda.Research and reports in urology · 2025Article
- Long-term outcomes of high-dose-rate brachytherapy and external beam radiotherapy without hormone therapy for high-risk localized prostate cancer.Japanese journal of radiology · 2024Article
- Prognostic Factors in Prostate Cancer Associated with Ulcerative Colitis.Journal of clinical medicine · 2024Article
- Prostate cancer screening in African American men: a review of the evidence.Journal of the National Cancer Institute · 2024Review
- Updated prevalence of latent prostate cancer in Chinese population and comparison of biopsy results: An autopsy-based study.Innovation (Cambridge (Mass.)) · 2024Article
- Is early-onset cancer an emerging global epidemic? Current evidence and future implications.Nature reviews. Clinical oncology · 2022Review
- Assessment of bone health in patients with prostate cancer using cancer staging computed tomography.Journal of bone and mineral metabolism · 2022Article
- The Relationship Between PSA and Total Testosterone Levels in Men With Prostate Cancer.The journal of sexual medicine · 2022Article
- Real-world data in elderly men from Yokosuka City 15 years after introducing prostate-specific antigen-based population screening.Molecular and clinical oncology · 2022Article
- A comparison of clinicopathologic features of prostate cancer between Nigerian and South African black men.African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA) · 2022Article
- Development and internal validation of a prediction model of prostate cancer on initial transperineal template-guided prostate biopsy.BMC urology · 2021Article
- Review
- On the information hidden in a classifier distribution.Scientific reports · 2021Article
- Prostate cancer: Therapeutic prospect with herbal medicine.Current research in pharmacology and drug discovery · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
MATERIALS AND
methodsData from 58 autopsy studies of latent prostate cancer from 1898-2013 were identified and analyzed accounting for histopathological methods, which may have varied over time.
resultsProstate cancer is most prevalent in African descent men, less prevalent in European descent men, and least prevalent in Asian descent men. Fifty percent of Asian men have latent prostate tumors by 90. This 50% prevalence is reached by age 80 in Caucasians, and by age 60 in African descent men. While men are rarely diagnosed with prostate cancer before age 40, 4% of Asian men, 9% of Caucasian men, and 37% of African descent men have latent prostate cancer before age 40. However, prostate cancer is under-ascertained in Africa. An increase in prostate cancer prevalence was observed by observing historical trends in prostate cancer prevalence. This increase is only significant in men of European descent, who experienced a 0.3% increase in prostate cancer prevalence per calendar year since the 1930's (p = 0.043). Evaluation of incidence-prevalence-duration data suggest that men are living longer with prostate cancer in recent years, perhaps due to early detection and improved treatment. This information has relevance for the design of clinical trials of prostate cancer detection, chemoprevention and treatment, and has been incorporated into recent guidelines for the early detection of prostate cancer and biopsy recommendations.
conclusionsProstate cancer is common at all ages and varies by race, and prevalence is increasing over time. Autopsy-based prevalence data provide a means of examining historical trends and comparison of diverse demographic groups and help guide clinical practice and trial design for the diagnosis and treatment of prostate cancer.
Indexed as
Identifiers
25347377PMC4955669W2411925042What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.