SynthesisThe Cochrane database of systematic reviews2014
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children.
Synthesis in The Cochrane database of systematic reviews, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Cyclamen europaeum extract for acute sinusitis.The Cochrane database of systematic reviews · 2018Pooled it
- Risk factors of acute bacterial paranasal sinusitis in children: a case control study.BMC infectious diseases · 2025Article
- Modelling Intra-Sinus Fluid Movements and Drainage Through Computational Fluid Dynamics Before and After Maxillary Sinus Augmentation: A Simulation-Based Pilot Study.Journal of clinical medicine · 2024Article
- Pharmacists' Attitudes Towards Long-Term Use of Nasal Decongestants: A Cross-Sectional Study.Journal of multidisciplinary healthcare · 2024Article
- A multicenter survey on the effectiveness of nasal irrigation devices in rhinosinusitis patients.Laryngoscope investigative otolaryngology · 2020Article
- Article
- Decongestants, antihistamines and nasal irrigation for acute sinusitis in children.Paediatrics & child health · 2016Article
- Position statement of the Brazilian Academy of Rhinology on the use of antihistamines, antileukotrienes, and oral corticosteroids in the treatment of inflammatory sinonasal diseases.Brazilian journal of otorhinolaryngologyReview
Corrections and comments
- Update of
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis has not been systematically evaluated.
objectivesTo determine the efficacy of decongestants, antihistamines or nasal irrigation in improving symptoms of acute sinusitis in children. SEARCH
methodsWe searched CENTRAL (2014, Issue 5), MEDLINE (1950 to June week 1, 2014) and EMBASE (1950 to June 2014). SELECTION CRITERIA: We included randomized controlled trials (RCTs) and quasi-RCTs, which evaluated children younger than 18 years of age with acute sinusitis, defined as 10 to 30 days of rhinorrhea, congestion or daytime cough. We excluded trials of children with chronic sinusitis and allergic rhinitis. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed each study for inclusion. MAIN
resultsOf the 662 studies identified through the electronic searches and handsearching, none met all the inclusion criteria. AUTHORS'
conclusionsThere is no evidence to determine whether the use of antihistamines, decongestants or nasal irrigation is efficacious in children with acute sinusitis. Further research is needed to determine whether these interventions are beneficial in the treatment of children with acute sinusitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.