Evidence map›Paper›PMID 25346860›Full record

ArticleJournal of AIDS and HIV research (Online)2012

Is serious mental illness associated with earlier death among persons with HIV? Ten year follow up in Maryland Medicaid Recipients.

Geetanjali Chander, YiYi Zhang, Susan dosReis, Donald M Steinwachs, Daniel E Ford, Eliseo Guallar, Gail Daumit

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of AIDS and HIV research (Online), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Geetanjali ChanderJohns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD.
YiYi ZhangJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Susan dosReisUniversity of Maryland School of Pharmacy, Baltimore, MD.
Donald M SteinwachsJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Daniel E FordJohns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD.
Eliseo GuallarJohns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.
Gail DaumitJohns Hopkins Medical Institutions, Johns Hopkins University, Baltimore, MD.
Johns Hopkins University · US

Funding

IMPLEMENTATION RESEARCH INSTITUTE FOR MENTAL HEALTH SERVICES IRI-MHSR25MH080916 · NIMH · WASHINGTON UNIVERSITY · PI Byron James Powell · 2009 to 2026
$3.7M
Preventable Mortality in Maryland Medicaid SMIR01MH074070 · NIMH · JOHNS HOPKINS UNIVERSITY · PI DAUMIT, GAIL L. · 2006 to 2009
$1.4M
Alcohol and Psychiatric Comorbidity in HIV+ WomenK23AA015313 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI · 2005 to 2009
$875k
Developing and Translating Interventions to Decrease Mortality Disparities in SMIK24MH093763 · NIMH · JOHNS HOPKINS UNIVERSITY · PI DAUMIT, GAIL L. · 2012 to 2016
$830k
NIAAA NIH HHS K23 AA015313NIMH NIH HHS K24 MH093763NIMH NIH HHS R01 MH074070NIMH NIH HHS R25 MH080916
6 · The paper itself

Abstract

BACKGROUND/

objectiveIn the general population serious mental illness (SMI) is associated with earlier mortality. The objective of this study was to determine if SMI was associated with an increased risk of death among Maryland Medicaid beneficiaries with HIV.

methodsThis was a retrospective cohort study of adult Maryland Medicaid recipients with HIV receiving antiretroviral therapy (ART) after January 1, 1997. SMI was defined as a specialty mental health visit and an ICD-9 diagnosis of 1) schizophrenia or related psychoses, 2) bipolar disorder or 3) major depressive disorder. Cox proportional hazards regression models were used to estimate the hazard ratios for total mortality. Analyses were adjusted for demographic characteristics, % days on ART, outpatient visits and comorbid medical conditions.

resultsOverall, 623 individuals received ART after treatment inception. The total number of deaths was 278, out of which 60 deaths were in the SMI group (38.5%) and 211 in the non-SMI group (45%) (p=0.05). In multivariable analysis, SMI was not associated with mortality. Increasing age, AIDS defining illness, renal failure, cerebrovascular disease, congestive heart failure, chronic liver disease and substance abuse were independently associated with mortality, while increased percent days of HIV medication use and number of outpatient medical visits were associated with improved survival.

conclusionsIn this sample, SMI is not associated with earlier death in patients with HIV infection. ART use and primary care engagement among HIV infected individuals are associated with improved survival irrespective of an SMI diagnosis.

Indexed as

HIVSMISurvival

Identifiers

PMID25346860
PMCPMC4208664
OpenAlexW2283379422

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.