ReviewFrontiers in microbiology2014
The role of hormones on Toxoplasma gondii infection: a systematic review.
Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Review
- Article
- Protective Effect of S-Methylcysteine Against Toxoplasma gondii-Induced Reproductive Toxicity in Female Albino Rats.Acta parasitologica · 2025Article
- Discovery of host genetic factors through multi-locus GWAS against toxoplasmosis in sheep: addressing one health perspectives.BMC veterinary research · 2025Article
- Tannin alleviated reproductive dysfunction in pregnant ewes infected withFrontiers in veterinary science · 2025Article
- Follow-Up Study of 17-β Estradiol, Prolactin and Progesterone with the Kinetics and Prevalence ofCurrent issues in molecular biology · 2024Article
- Effective factors in the pathogenesis ofHeliyon · 2024Review
- Toxoplasmosis Screening during Pregnancy in a Romanian Infectious Diseases Tertiary Center: Results of a 15 Years Follow-Up Program.Microorganisms · 2023Article
- Seroprevalence of Toxoplasma gondii infection among patients of a tertiary hospital in Guangzhou, Guangdong province, PR China.PloS one · 2023Article
- Parasitic infection increases risk-taking in a social, intermediate host carnivore.Communications biology · 2022Article
- Toxoplasmosis: Targeting neurotransmitter systems in psychiatric disorders.Metabolic brain disease · 2022Review
- Effect of 17β-Estradiol, Progesterone, and Tamoxifen on Neurons Infected withMicroorganisms · 2021Article
- Peripheral and placental immune responses in sheep after experimental infection with Toxoplasma gondii at the three terms of gestation.Veterinary research · 2019Article
- Transcriptional Analysis Shows a Robust Host Response toInfection and immunity · 2019Article
- The relation of serum prolactin levels andInternational journal of general medicine · 2019Article
- Testicular toxoplasmosis in a 26-year-old immunocompetent man.BMJ case reports · 2018Article
- In Vitro Anti-Toxoplasma gondii and Antimicrobial Activity of Amides Derived from Cinnamic Acid.Molecules (Basel, Switzerland) · 2018Article
- Estradiol Attenuates the Severity of PrimaryFrontiers in immunology · 2018Article
- Abscisic Acid as Pathogen Effector and Immune Regulator.Frontiers in plant science · 2017Review
- Influence of Toxoplasma gondii Infection on Male Fertility: A Pilot Study on Immunocompetent Human Volunteers.Iranian journal of parasitologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxoplasma gondii is the causal agent of toxoplasmosis in which one third of the world's population has been infected. In pregnant women, it may cause abortion and severe damage to the fetal central nervous system. During pregnancy, the prevalence of toxoplasmosis increases throughout the second and third quarter of gestation, simultaneously progesterone and 17β-estradiol also increase. Thus, it has been suggested that these hormones can aggravate or reduce parasite reproduction. The aim of this study was reviewing the relationship between hormones and infection caused by T. gondii in several experimental animal models and humans, focused mainly on: (a) congenital transmission, (b) parasite reproduction, (c) strain virulence, (d) levels of hormone in host induced by T. gondii infection, and (e) participation of hormone receptors in T. gondii infection. Are the hormones specific modulators of T. gondii infection? A systematic review methodology was used to consult several databases (Pub Med, Lilacs, Medline, Science direct, Scielo, Ebsco, Sprinker, Wiley, and Google Scholar) dated from September, 2013 to March, 2014.
resultsThirty studies were included; eight studies in humans and 22 in animals and cell cultures. In the human studies, the most studied hormones were testosterone, progesterone, prolactin, and 17β-estradiol. Type I (RH and BK) and Type II (Prugniaud, SC, ME49, T45, P78, and T38) were the most frequent experimental strains.
conclusionsThirty-five years have passed since the first studies regarding T. gondii infection and its relationship with hormones. This systematic review suggests that hormones modulate T. gondii infection in different animal models. However, given that data were not comparable, further studies are required to determine the mechanism of hormone action in the T. gondii infectious process.
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