Evidence map›Paper›PMID 25346650›Full record

ArticleSleep medicine clinics2014

Advances in Positive Airway Pressure Treatment Modalities for Hypoventilation Syndromes.

Dan Combs, Safal Shetty, Sairam Parthasarathy

Open access · greenAbstract read
In one paragraph

Article in Sleep medicine clinics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Complementary roles of gasotransmitters CO and H2S in sleep apnea.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  4. Retrospective Assessment of Home Ventilation to Reduce Rehospitalization in Chronic Obstructive Pulmonary Disease.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2015
    Article
  5. Obesity Hypoventilation Syndrome.Current pulmonology reports · 2015
    Article
  6. Obesity hypoventilation syndrome: a current review.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dan CombsArizona Respiratory Center, University of Arizona, Tucson, AZ ; Department of Pediatrics, University of Arizona, Tucson, AZ.
Safal ShettyArizona Respiratory Center, University of Arizona, Tucson, AZ ; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine of University of Arizona, Tucson, AZ.
Sairam ParthasarathyArizona Respiratory Center, University of Arizona, Tucson, AZ ; Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine of University of Arizona, Tucson, AZ.
University of Arizona · US

Funding

Sleep Intervention During Acute Lung InjuryR01HL095748 · NHLBI · UNIVERSITY OF ARIZONA · PI PARTHASARATHY, SAIRAM · 2009 to 2013
$1.9M
NHLBI NIH HHS R01 HL095748
6 · The paper itself

Abstract

rationalePositive airway pressure therapy for hypoventilation syndromes can significantly improve health-related quality of life (HR-QOL), healthcare costs, and even mortality. The sleep-disordered breathing in such individuals are quite complex and require sophisticated devices with algorithms that are designed to accurately detect and effectively treat respiratory events that includes hypoventilation, upper airway obstruction, lower airway obstruction, central apneas and central hypopneas and reduce the work of breathing while maintaining breathing comfort.

objectivesThe therapeutic physiological rationale for the various advanced PAP modalities and the details about the principles of operation and technology implementation are provided here.

conclusionsThe physiological rationale for advanced PAP modalities is sound considering the complexity of sleep-disordered breathing in patients with hypoventilation syndromes. Although such devices are increasingly used in clinical practice, the supporting clinical evidence - specifically comparative-effectiveness studies in real-life conditions -- needs to be performed. Moreover, there is much opportunity for further refining these devices that include the ability of the device to reliably monitor gas-exchange, sleep-wakefulness state, and for reducing variability in device efficacy due to provider-selected device-settings.

Indexed as

algorithmsartificial respirationcontinuous positive airway pressureHypoventilation syndromeobesityobstructive sleep apneapositive airway pressuresleep

Identifiers

PMID25346650
PMCPMC4205540
OpenAlexW2013256387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.