Evidence map›Paper›PMID 25346613›Full record

ArticleCurrent organic chemistry2014

Quinone Methide Bioactivation Pathway: Contribution to Toxicity and/or Cytoprotection?

Judy L Bolton

Open access · greenAbstract read
In one paragraph

Article in Current organic chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 77 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Gas Delivery Relevant to Human Health using Porous Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Purple pigment fromJournal of food science and technology · 2019
    Article
  13. Safety of Aqueous Extract ofEvidence-based complementary and alternative medicine : eCAM · 2019
    Article
  14. Article
  15. Formation and biological targets of botanical o-quinones.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2018
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Judy L BoltonDepartment of Medicinal Chemistry and Pharmacognosy (M/C 781) College of Pharmacy University of Illinois at Chicago 833 S. Wood Street Chicago, Illinois 60612-7231.
University of Illinois Chicago · US

Funding

Van Breemen: Project 3; Botanical Dietary Supplements - Metabolism and Safety in Women (Van Breemen)P50AT000155 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PAULI, GUIDO F · 1999 to 2019
$30.4M
CARCINOGENIC METABOLITES FORMED FROM ANTIESTROGENSR01CA079870 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BOLTON, JUDY L · 1999 to 2013
$2.9M
Role of electrophilic/redox active quinoids in estrogen carcinogenesisR01CA130037 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BOLTON, JUDY L · 2007 to 2011
$1.4M
Carcinogenic Metabolites Formed from AntiestrogensR56CA079870 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BOLTON, JUDY L · 2008 to 2008
$216k
NCCIH NIH HHS P50 AT000155NCI NIH HHS R01 CA079870NCI NIH HHS R01 CA130037NCI NIH HHS R56 CA079870
6 · The paper itself

Abstract

The formation of quinone methides (QMs) from either direct 2-electron oxidation of 2- or 4-alkylphenols, isomerization of

Indexed as

bioactivationP450quinonequinone methideselective estrogen receptor modulators (SERMs)

Identifiers

PMID25346613
PMCPMC4204646
OpenAlexW2019190381

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.