Evidence map›Paper›PMID 25345807›Full record

ReviewCellular & molecular immunology2015

Ubiquitin-mediated NFκB degradation pathway.

Huimin Xu, Mengli You, Haifeng Shi, Yongzhong Hou

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Ubiquitination of CD47 Regulates Innate Anti-Tumor Immune Response.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Article
  4. NArchives of microbiology · 2024
    Article
  5. Pig-Derived ProbioticAnimals : an open access journal from MDPI · 2024
    Article
  6. Review
  7. Dual function of activated PPARγ by ligands on tumor growth and immunotherapy.Medical oncology (Northwood, London, England) · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. RBM23 Drives Hepatocellular Carcinoma by Activating NF-BioMed research international · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Cell Clearing Systems Bridging Neuro-Immunity and Synaptic Plasticity.International journal of molecular sciences · 2019
    Review
  17. Review
  18. Article
  19. Effect of Kangshuanyihao Formula on the Inflammatory Reaction and SIRT1/TLR4/NF-Evidence-based complementary and alternative medicine : eCAM · 2017
    Article
  20. Naoxintong/PPAREvidence-based complementary and alternative medicine : eCAM · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huimin Xu
Mengli You
Haifeng Shi
Yongzhong Hou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nuclear factor κB (NFκB) transcription factor plays critical roles in inflammation and immunity. The dysregulation of NFκB is associated with inflammatory and autoimmune diseases and cancer. NFκB activation is negatively regulated by the ubiquitin-dependent proteasomal degradation pathway. In the present review, we discuss recent advances in our understanding of how ubiquitin ligases regulate the NFκB degradation pathway.

Indexed as

Adaptor Proteins, Signal TransducingAutoimmune DiseasesGene Expression RegulationHumansNeoplasmsNF-kappa Bp300-CBP-Associated Factorp300-CBP Transcription FactorsProteasome Endopeptidase ComplexProtein StabilityProteolysisSignal TransductionUbiquitinUbiquitin-Protein LigasesAdaptor Proteins, Signal TransducingCOMMD1 protein, humanNF-kappa Bp300-CBP-Associated Factorp300-CBP Transcription FactorsProteasome Endopeptidase ComplexUbiquitinUbiquitin-Protein Ligases

Identifiers

PMID25345807
PMCPMC4716629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.