ArticleThe Laryngoscope2015
Outcomes of serial dilation for high-grade radiation-related esophageal strictures in head and neck cancer patients.
Article in The Laryngoscope, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Guideline
- Predictive Factors for Esophageal Stricture Following Definitive Chemoradiotherapy in Esophageal Carcinoma.Journal of gastrointestinal cancer · 2025Article
- Safety of a Novel Upper Esophageal Sphincter Balloon Dilator.The Laryngoscope · 2025Article
- Design and Material Characterization of an Inflatable Vaginal Dilator.Materials (Basel, Switzerland) · 2024Article
- Developing a Tracheal Rendezvous Procedure for Complete High Subglottic Stenosis.Life (Basel, Switzerland) · 2023Article
- GERD-related chronic cough: Possible mechanism, diagnosis and treatment.Frontiers in physiology · 2022Review
- Outcomes of Combined Antegrade-Retrograde Dilations for Radiation-Induced Esophageal Strictures in Head and Neck Cancer Patients.Dysphagia · 2021Article
- Esophageal stenosis in head and neck cancer patients: Imaging's accuracy to predict dilation response.Laryngoscope investigative otolaryngology · 2021Article
- Benign Pharyngoesophageal Strictures: Increasingly Encountered and Still a Challenge.GE Portuguese journal of gastroenterology · 2018Article
- Endoscopic Dilation of Pharyngoesophageal Strictures: There Are More Dimensions than a Diameter.GE Portuguese journal of gastroenterology · 2018Article
- Improved symptomatic, functional, and fluoroscopic outcomes following serial "series of three" double-balloon dilation for cricopharyngeus muscle dysfunction.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2018Article
- Presentation and Epidemiology of Gastroesophageal Reflux Disease.Gastroenterology · 2018Review
- Endoscopic dilation of complete oesophageal obstructions with a combined antegrade-retrograde rendezvous technique.World journal of gastroenterology · 2016Observational
- Endoscopic Approach to Reopening a Completely Obstructed Esophagus.Gastroenterology & hepatology · 2015Article
- Recurrent Complete Pharyngo-Oesophageal Stricture Treated by Multidisciplinary Anterograde-Retrograde Endoscopic Dilation.Case reports in gastroenterologyArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectives/hypothesisDysphagia and esophageal stricture are frequent consequences of treatment for head and neck cancer. This study examines the effectiveness of the anterograde-retrograde rendezvous procedure and serial dilations in reestablishing esophageal patency to allow return to oral diet and gastrostomy tube removal in a cohort of patients with complete or near-complete esophageal stricture following nonsurgical cancer treatment. STUDY
designRetrospective review of patients treated with radiation therapy with or without concurrent chemotherapy presented with complete or near-complete esophageal stricture. Patients underwent serial dilations using combined anterograde-retrograde dilation (rendezvous) techniques.
methodsMedical records of patients having undergone treatment between 2006 and 2012 were reviewed, and semistructured interviews were also conducted to determine current swallowing function and actual patient experience. The primary outcome was swallowing improvement that allowed for return to oral diet and/or gastrostomy tube removal. Outcomes were compared between patients with complete and near-complete (<5 mm in diameter) strictures and univariate analysis performed to identify associations between patient, cancer, and treatment characteristics on odds of gastrostomy tube removal.
resultsTwenty-four patients (median age 59.5 years, 63% male, 91% Caucasian) underwent treatment. Fifty percent of patients had complete occlusion of the esophageal lumen. The majority of patients (92%) underwent either anterograde (54%) or combined antero-retrograde (38%) approach. Following a median (interquartile range) of 9 (6-20) dilation sessions, 42% of patients were able to return to an oral diet and/or had their gastrostomy tube removed. This outcome was independent of whether the stricture was complete or near complete (P = .67). Of patients who had their gastrostomy tubes removed, only 33.3% had ever smoked, compared to 92.3% of those whose tubes were not discharged (P = .007).
conclusionsRecannulation is possible even in cases of complete or near-complete stricture. Several factors appear to impact the likelihood of successful outcome, but in this study, only patients with a history of smoking had a significantly lower likelihood of return to full oral diet.
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