ArticleNature nanotechnology2014
Long-range charge transport in single G-quadruplex DNA molecules.
Article in Nature nanotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
67 citing papers in PubMed, 261 citations in OpenAlex.
- Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication.Angewandte Chemie (International ed. in English) · 2026Article
- Rational Polyligand Design for G-Quadruplex Multimer Stabilization.Journal of chemical information and modeling · 2026Article
- Unravelling the noncanonical extracellular DNA structures in biofilm and NETosis.Nucleic acids research · 2026Review
- Enhancing G-quadruplex-based DNA nanotechnology: new lipophilic DNA G-quadruplexes with TBDPS modifications.RSC advances · 2025Article
- TNF-α exacerbates calcium influx via voltage-gated calcium channels in breast cancer cells: a nanoscale multimodal AFM study.Frontiers in cell and developmental biology · 2025Article
- Entangled World of DNA Quadruplex Folds.ACS omega · 2024Article
- AgNanomaterials (Basel, Switzerland) · 2024Article
- Understanding self-assembly at molecular level enables controlled design of DNA G-wires of different properties.Nature communications · 2022Article
- Nanocellulose Composites as Smart Devices With Chassis, Light-Directed DNA Storage, Engineered Electronic Properties, and Chip Integration.Frontiers in bioengineering and biotechnology · 2022Article
- Electron Holes in G-Quadruplexes: The Role of Adenine Ending Groups.International journal of molecular sciences · 2021Article
- Role of Order in the Mechanism of Charge Transport across Single-Stranded and Double-Stranded DNA Monolayers in Tunnel Junctions.Journal of the American Chemical Society · 2021Article
- Molecular electronics behaviour of L-aspartic acid using symmetrical metal electrodes.Journal of molecular modeling · 2021Article
- LCAO Electronic Structure of Nucleic Acid Bases and Other Heterocycles and Transfer Integrals in B-DNA, Including Structural Variability.Materials (Basel, Switzerland) · 2021Article
- A new G-triplex-based strategy for sensitivity enhancement of the detection of endonuclease activity and inhibition.RSC advances · 2021Article
- Complex Metal Nanostructures with Programmable Shapes from Simple DNA Building Blocks.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Facile room-temperature self-assembly of extended cation-free guanine-quartet network on Mo-doped Au(111) surface.Nanoscale advances · 2021Article
- Reversible Photoisomerization in Thin Surface Films from Azo-Functionalized Guanosine Derivatives.ACS omega · 2021Article
- Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Article
- Backbone charge transport in double-stranded DNA.Nature nanotechnology · 2020Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors at 7 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
DNA and DNA-based polymers are of interest in molecular electronics because of their versatile and programmable structures. However, transport measurements have produced a range of seemingly contradictory results due to differences in the measured molecules and experimental set-ups, and transporting significant current through individual DNA-based molecules remains a considerable challenge. Here, we report reproducible charge transport in guanine-quadruplex (G4) DNA molecules adsorbed on a mica substrate. Currents ranging from tens of picoamperes to more than 100 pA were measured in the G4-DNA over distances ranging from tens of nanometres to more than 100 nm. Our experimental results, combined with theoretical modelling, suggest that transport occurs via a thermally activated long-range hopping between multi-tetrad segments of DNA. These results could re-ignite interest in DNA-based wires and devices, and in the use of such systems in the development of programmable circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.