Evidence map›Paper›PMID 25344657›Full record

ArticleMedical microbiology and immunology2015

A French multicentric study and review of pulmonary Nocardia spp. in cystic fibrosis patients.

Verónica Rodriguez-Nava, Stéphane Durupt, Sandra Chyderiotis, Anne-Marie Freydière, Judith Karsenty, Michèle de Montclos, Philippe Reix, Isabelle Durieu, Raphaele Nove-Josserand, Raphael Chiron and 12 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Medical microbiology and immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Updated Review onClinical microbiology reviews · 2022
    Review
  6. Article
  7. Microbial risk assessment ofComputational and structural biotechnology journal · 2021
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 10 institutions in 1 country.

Verónica Rodriguez-NavaUniversité de Lyon, Lyon, France.
Stéphane Durupt
Sandra Chyderiotis
Anne-Marie Freydière
Judith Karsenty
Michèle de Montclos
Philippe Reix
Isabelle Durieu
Raphaele Nove-Josserand
Raphael Chiron
François Bremont
Laurent Têtu
Marlène Murris
Dominique Terru
Sylvain Godreuil
Emmanuelle Bergeron
Jean Freney
Patrick Boiron
François Vandenesch
Hélène Marchandin
Christine Segonds
Anne Doléans-Jordheim
Hospices Civils de Lyon · FRHôpital Arnaud de Villeneuve · FRVetAgro Sup · FRHôpital Larrey · FRHôpital Lyon Sud · FRUniversité Claude Bernard Lyon 1 · FRCentre National de la Recherche Scientifique · FRHôpital des Enfants · FRHôpital Femme Mère Enfant · FRHôpital Purpan · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some bacterial species recovered from the airways of cystic fibrosis (CF) patients are indisputably associated with lung infections, whereas the clinical relevance of others, such as Nocardia spp., remains unclear. Sixteen French CF cases of colonization/infection with Nocardia spp. were reviewed in order to evaluate the epidemiology, the clinical impact and the potential treatment of these bacteria, and results were compared to those of the literature. Five Nocardia species were identified, Nocardia cyriacigeorgica being the major species (50 % of cases). At first isolation, Nocardia was the sole pathogen recovered in six patients. Seven patients presented pulmonary exacerbation. For 12 patients, antimicrobial treatment against Nocardia was started immediately, mainly based on cotrimoxazole (6 of the 12 cases). In this study, we highlight the heterogeneity of the clinical management of Nocardia spp. in CF. Guidelines for the clinical management of Nocardia infections in CF patients are proposed.

Indexed as

AdolescentAdultAgedAnti-Bacterial AgentsCarrier StateChildChild, PreschoolCystic FibrosisFranceHumansInfantInfant, NewbornMaleNocardiaNocardia InfectionsPneumonia, BacterialAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID25344657
OpenAlexW2037602078

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.