ArticlePloS one2014
Herpes zoster is associated with prior statin use: a population-based case-control study.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between statin use and herpes zoster: systematic review and meta-analysis.BMJ open · 2019Pooled it
- Lipids, lipid-lowering drugs and the risk of herpes zoster: a Mendelian randomization study.Archives of dermatological research · 2025Article
- Article
- Risk Factors for Herpes Zoster Infection: A Meta-Analysis.Open forum infectious diseases · 2020Review
- Statin therapy and herpes virus reactivation-response to Zuin et al. paper.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- Recurrence Rate of Herpes Zoster and Its Risk Factors: a Population-based Cohort Study.Journal of Korean medical science · 2019Article
- Herpes zoster infection and statins: which implications in clinical practice?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Review
- Do outpatient statins and ACEIs/ARBs have synergistic effects in reducing the risk of pneumonia? A population-based case-control study.PloS one · 2018Article
- Article
- Herpes Zoster in Persons Living with HIV-1 Infection: Viremia and Immunological Defects Are Strong Risk Factors in the Era of Combination Antiretroviral Therapy.Frontiers in public health · 2018Article
- Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific.BMC infectious diseases · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigated the association between statin use and herpes zoster (HZ) occurrence in a population-based case-control study.
methodsStudy subjects were retrieved from the Taiwan Longitudinal Health Insurance Database 2000. This study included 47,359 cases with HZ and 142,077 controls. We performed conditional logistic regression analyses to calculate the odds ratio (OR) to present the association between HZ and having previously been prescribed statin.
resultsWe found that 13.0% of the sampled subjects had used statins, at 15.5% and 12.1% for cases and controls, respectively (p<0.001). A conditional logistic regression analysis suggested that the adjusted OR of being a statin user before the index date for cases was 1.28 (95% confidence interval (CI): 1.24∼1.32) compared to controls. Subjects aged 18∼44 years had the highest adjusted OR for prior statin use among cases compared to controls (OR: 1.69; 95% CI: 1.45∼1.92). Furthermore, we found that the ORs of being a regular and irregular statin user before the index date for cases were 1.32 (95% CI: 1.27∼1.38) and 1.23 (95% CI: 1.181.29), respectively, compared to controls.
conclusionsWe concluded that prior statin use was associated with HZ occurrence.
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