Evidence map›Paper›PMID 25342997›Full record

ReviewTherapeutic advances in musculoskeletal disease2014

Medication-induced osteoporosis: screening and treatment strategies.

Keshav Panday, Amitha Gona, Mary Beth Humphrey

Open access · bronzeAbstract readReview
In one paragraph

Review in Therapeutic advances in musculoskeletal disease, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 4 syntheses or guidelines pooled it, 188 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Fracture risk in oral glucocorticoid users: a Bayesian meta-regression leveraging control arms of osteoporosis clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Review
  10. Article
  11. Drug-Induced Osteoporosis.Journal of clinical medicine · 2026
    Review
  12. Review
  13. Article
  14. Review
  15. Potential ofChinese herbal medicines · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Keshav PandayDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Amitha GonaDepartment of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Mary Beth HumphreyDepartment of Medicine, University of Oklahoma Health Sciences Center, and Veterans Affairs Medical Center, 975 NE 10th St, BRC209, Oklahoma City, OK 73104, USA.
University of Oklahoma Health Sciences Center · US

Funding

Mechanism of ITAM Signal Regulation in OsteoclastsR01DE019398 · NIDCR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI HUMPHREY, MARY BETH · 2008 to 2012
$1.3M
NIDCR NIH HHS R01 DE019398
6 · The paper itself

Abstract

Drug-induced osteoporosis is a significant health problem and many physicians are unaware that many commonly prescribed medications contribute to significant bone loss and fractures. In addition to glucocorticoids, proton pump inhibitors, selective serotonin receptor inhibitors, thiazolidinediones, anticonvulsants, medroxyprogesterone acetate, aromatase inhibitors, androgen deprivation therapy, heparin, calcineurin inhibitors, and some chemotherapies have deleterious effects on bone health. Furthermore, many patients are treated with combinations of these medications, possibly compounding the harmful effects of these drugs. Increasing physician awareness of these side effects will allow for monitoring of bone health and therapeutic interventions to prevent or treat drug-induced osteoporosis.

Indexed as

anticonvulsantsaromatasecalcineuringlucocorticoidsmedroxyprogesteroneosteoporosisproton pumpserotoninthiazolidinediones

Identifiers

PMID25342997
PMCPMC4206646
OpenAlexW2005836587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.