Evidence map›Paper›PMID 25342882›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2014

Findings of secondary corneal amyloidosis with ultrahigh-resolution optical coherence tomography.

Kaoru Araki-Sasaki, Yasuhiro Osakabe, Hideki Fukuoka, Ryuichi Ideta, Koji Hirano

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Kaoru Araki-SasakiDepartment of Ophthalmology, Japan Community Health Care Organization, Hoshigaoka Medical Center, Hirakata, Japan.
Yasuhiro OsakabeDepartment of Molecular Pathology, Tokyo Medical University, Tokyo, Japan.
Hideki FukuokaDepartment of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ryuichi IdetaIdeta Eye Hospital, Kumamoto, Japan.
Koji HiranoDepartment of Ophthalmology, Ban Buntane Hotokukai Hospital, School of Medicine, Fujita Health University, Nagoya, Japan.
Fujita Health University · JPHoshigaoka Medical Center · JPKyoto Prefectural University of Medicine · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe observations by ultrahigh-resolution optical coherence tomography (OCT) in a secondary corneal amyloidosis (SCA) patient with histological analysis of excised tissue. A unique finding under OCT of her fellow eye is also described. CASE: A 39-year-old female had suffered from trichiasis in both of her eyes for more than 30 years. Slit-lamp examination showed a milky-white soft mass on her left cornea and a linear opacity on the fellow cornea at the cilia-attached region. OCT demonstrated the presence of a mass region within a thin epithelial layer and no destruction of Bowman's layer in her left cornea. In the fellow cornea, which exhibited a linear opacity, a high-density spot in Bowman's layer was observed at the cilia-attached region covered by the epithelial layer, with normal thickness. Histological examination of the excised cornea showed that the mass was positive with both Congo red and antilactoferrin antibody.

conclusionSCA, amyloid gradually accumulates above Bowman's layer, occupying the epithelial layer, with no destruction of Bowman's layer until the advanced stage. A high-density spot in Bowman's layer might be the first stage of SCA.

Indexed as

cornealactoferrinOCTsecondary corneal amyloidosis

Identifiers

PMID25342882
PMCPMC4206355
OpenAlexW1989817603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.