Evidence map›Paper›PMID 25342771›Full record

ArticleCirculation research2014

Letter by Murry et al regarding article, "Embryonic stem cell-derived cardiac myocytes are not ready for human trials".

Charles E Murry, James J H Chong, Michael A Laflamme

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Charles E MurryCenter for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA.
James J H ChongDepartment of Cardiology, Westmead Hospital, Sydney, NSW, AustraliaSchool of Medicine, University of Sydney, Sydney, NSW, AustraliaWestmead Millennium Institute for Medical Research, Sydney, NSW, Australia.
Michael A LaflammeCenter for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA.

Funding

Washington National Primate Research CenterP51OD010425 · OD · UNIVERSITY OF WASHINGTON · PI Mari Ostendorf · 2012 to 2026
$201.8M
Self Renewal and Differentiation of Human Embryonic Stem CellsP01GM081619 · NIGMS · UNIVERSITY OF WASHINGTON · PI MURRY, CHARLES E · 2007 to 2017
$20.6M
Vascularization and Growth of Human Myocardial GraftsP01HL094374 · NHLBI · UNIVERSITY OF WASHINGTON · PI MURRY, CHARLES E · 2010 to 2014
$14.5M
Expansion of cardiac and hematopoietic progenitors by Wnt and NotchU01HL100405 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI EPSTEIN, JONATHAN A., MORRISEY, EDWARD E · 2009 to 2015
$8.1M
Cell-Based Cardiac RepairR01HL084642 · NHLBI · UNIVERSITY OF WASHINGTON · PI MURRY, CHARLES E · 2007 to 2014
$4.9M
Integration and Arrhythmia Suppression with hESC-Derived Cardiomyocyte GraftsR01HL117991 · NHLBI · UNIVERSITY OF WASHINGTON · PI LAFLAMME, MICHAEL ALAN · 2013 to 2015
$1.2M
NHLBI NIH HHS P01 HL094374NHLBI NIH HHS R01 HL084642NHLBI NIH HHS R01 HL117991NHLBI NIH HHS U01 HL100405NIGMS NIH HHS P01 GM081619NIH HHS P51 OD010425
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeartRegenerationAnimalsEmbryonic Stem CellsHumansMaleMyocardial InfarctionMyocytes, Cardiac

Identifiers

PMID25342771
PMCPMC4209407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.