Evidence map›Paper›PMID 25342557›Full record

ArticleCell research2015

Another twist in the histone memory code.

Sheena Josselyn, Paul W Frankland

Abstract readComment
In one paragraph

Article in Cell research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sheena Josselyn1] Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada [2] Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada [3] Department of Psychology, University of Toronto, Toronto, Ontario M5S 3GM, Canada [4] Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
Paul W Frankland1] Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada [2] Institute of Medical Science, University of Toronto, Toronto, Ontario M5S 1A8, Canada [3] Department of Psychology, University of Toronto, Toronto, Ontario M5S 3GM, Canada [4] Department of Physiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription is a highly regulated process and several studies have examined the role of transcription factors and various epigenetic regulators in memory formation. In a recent paper in Nature, Zokvic and colleagues show an important role for a novel regulator of chromatin structure (the incorporation of histone variants) in memory formation.

Indexed as

Epigenesis, GeneticAnimalsHistonesMaleMemoryHistones

Identifiers

PMID25342557
PMCPMC4650565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.