Evidence map›Paper›PMID 25342552›Full record

ArticleMolecules (Basel, Switzerland)2014

Influence of sulfur fumigation on the chemical constituents and antioxidant activity of buds of Lonicera japonica.

Ai-Li Guo, Liang-Mian Chen, Yan-Min Wang, Xiao-Qian Liu, Qi-Wei Zhang, Hui-Min Gao, Zhi-Min Wang, Wei Xiao, Zhen-Zhong Wang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Frontiers in pharmacology · 2023
    Review
  5. Article
  6. Potential Application ofFrontiers in microbiology · 2021
    Review
  7. Article
  8. Lonicerae japonicae flos and Lonicerae flos: a systematic review of ethnopharmacology, phytochemistry and pharmacology.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2020
    Review
  9. Article
  10. Article
  11. A Simple, Rapid, and Practical Method for DistinguishingMolecules (Basel, Switzerland) · 2019
    Article
  12. Article
  13. Article
  14. Antioxidant and anti-inflammatory activities ofIndustrial crops and products · 2016
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ai-Li GuoInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. guoaililu@126.com.
Liang-Mian ChenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. chris-clm@163.com.
Yan-Min WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. wangyanmin@126.com.
Xiao-Qian LiuInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. lianyu1127@126.com.
Qi-Wei ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. zhangqw1955@163.com.
Hui-Min GaoInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. huimin_gao@126.com.
Zhi-Min WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. zhmw123@263.net.
Wei XiaoJiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang 222001, China. wzhzh-nj@tom.com.
Zhen-Zhong WangJiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang 222001, China. wzhzh-nj@tom.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNKanion Pharmaceutical (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lonicera japonica flos is widely used as a pharmaceutical resource and a commonly-employed ingredient in healthy food, soft beverages and cosmetics in China. Sometimes, sulfur fumigation is used during post-harvest handling. In this study, a comprehensive comparison of the chemical profile between sun-dried and sulfur-fumigated samples was conducted by HPLC fingerprints and simultaneous quantification of nine constituents, including secologanic acid, along with another eight usually-analyzed markers. Secologanic acid was destroyed, and its sulfonates were generated, whereas caffeoylquinic acids were protected from being oxidized. The residual sulfur dioxide in sulfur-fumigated samples was significantly higher than that in sun-dried samples, which might increase the potential incidence of toxicity to humans. Meanwhile, compared with sun-dried samples, sulfur-fumigated samples have significantly stronger antioxidant activity, which could be attributed to the joint effect of protected phenolic acids and flavonoids, as well as newly-generated iridoid sulfonates.

Indexed as

AntioxidantsChinaChromatography, High Pressure LiquidFlavonoidsFumigationIridoid GlycosidesLoniceraPlant ExtractsQuinic AcidSulfurSulfur DioxideAntioxidantscaffeoylquinic acidFlavonoidsIridoid GlycosidesPlant ExtractsQuinic AcidSulfurSulfur Dioxide

Identifiers

PMID25342552
PMCPMC6271180
OpenAlexW2121987800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.